WormBase Tree Display for Gene: HGNC:9991
expand all nodes | collapse all nodes | view schema
HGNC:9991 | Identity | Name | CGC_name | Rgs1 | Inferred_automatically | AGR_import |
---|---|---|---|---|---|---|
Other_name (12) | ||||||
Public_name | Rgs1 | |||||
DB_info | Database | HGNC | id | 9991 | ||
AGR | cURI | HGNC:9991 | ||||
EnsEMBL | ENSEMBL_geneID | ENSG00000090104 | ||||
UniProt | UniProt_AC | Q08116 | ||||
Species | Homo sapiens | |||||
Status | Live | |||||
Gene_info | Biotype | SO:0001217 | ||||
Ortholog | WBGene00004351 | Caenorhabditis elegans | From_analysis | OMA | ||
OrthoFinder | ||||||
Panther | ||||||
WBGene00004350 | Caenorhabditis elegans | From_analysis | OrthoFinder | |||
Panther | ||||||
PhylomeDB | ||||||
WBGene00004353 | Caenorhabditis elegans | From_analysis | OrthoFinder | |||
Panther | ||||||
PhylomeDB | ||||||
WBGene00021988 | Caenorhabditis elegans | From_analysis | OMA | |||
OrthoFinder | ||||||
Panther | ||||||
Structured_description | Automated_description | This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq, Jul 2008] | Inferred_automatically | AGR_import |