WormBase Tree Display for Gene: WBGene00005016
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| WBGene00005016 | SMap | S_parent | Sequence | B0491 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | sqt-1 | Person_evidence | WBPerson153 | |||||
| Sequence_name | B0491.2 | ||||||||
| Molecular_name | B0491.2 | ||||||||
| B0491.2.1 | |||||||||
| CE02104 | |||||||||
| B0491.2.2 | |||||||||
| Other_name | rol-5 | ||||||||
| Rol | |||||||||
| CELE_B0491.2 | Accession_evidence | NDB | BX284602 | ||||||
| Public_name | sqt-1 | ||||||||
| DB_info | Database | AceView | gene | 2L626 | |||||
| WormQTL | gene | WBGene00005016 | |||||||
| WormFlux | gene | WBGene00005016 | |||||||
| NDB | locus_tag | CELE_B0491.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00005016|UniProtKB=P12114 | |||||||
| family | PTHR24637 | ||||||||
| NCBI | gene | 174731 | |||||||
| RefSeq | protein | NM_001383951.2 | |||||||
| SwissProt | UniProtAcc | P12114 | |||||||
| TREEFAM | TREEFAM_ID | TF321978 | |||||||
| UniProt_GCRP | UniProtAcc | P12114 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:37 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | sqt | ||||||||
| Reference_allele | WBVar00242664 | ||||||||
| Allele (41) | |||||||||
| Legacy_information | scl : homozygotes short dumpyish in adult and L4; roll in L3; scl/+ non-dumpy right-handed rollers in adult L4 L3. ES3 ME1. NA (dominant) > 10 (su1005 e1584 : resemble scl) e1350 (recessive dumpy) etc.). Also recessive alleles e.g. sc13 (pka rol-5) : adults L3 and L4 larvae left-handed rollers. ES3 (adult late larvae). NA > 15 (sc101 (long) sc33ts (at 25x rolls only in adult at 16x wildtype) etc. Complex complementation patterns. Null phenotype probably wildtype. | ||||||||
| See sqt-1. | |||||||||
| See also e1350, e1584, e1587 | |||||||||
| [C.elegansII] sclsd : homozygotes short, dumpyish in adult and L4; roll in L3; scl/+ non-dumpy right-handed rollers in adult, L4,L3. ES3 ME1. OA>10 (dominant): su1005, e1584 (resemble scl), e1350 (recessive dumpy) etc.). Also recessive alleles e.g. sc13 (pka rol-5, adults L3 and L4 larvae left-handed rollers. ES3 (adult, late larvae)), sc101 (long), sc33ts (at 25C rolls only in adult at 16C wildtype) etc. Complex complementation patterns. Null phenotype probably wildtype. Cloned: encodes 32 kD collagen, sqt-1 family includes rol-6; expressed each larval stage, 4 - 2.5 hr pre-lethargus. [Kramer et al. 1988; Park and Kramer 1994; CH; IA] | |||||||||
| Strain (63) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00039146 | ||||||||
| 00039147 | |||||||||
| 00039148 | |||||||||
| 00039149 | |||||||||
| 00039150 | |||||||||
| 00039151 | |||||||||
| 00113424 | |||||||||
| Ortholog (21) | |||||||||
| Paralog (16) | |||||||||
| Structured_description | Concise_description | sqt-1 encodes a cuticle collagen; during larval and adult development, sqt-1 activity is required, likely redundantly, for normal cuticle, and hence organismal, morphology; sqt-1 mRNA abundance oscillates during larval development, peaking at one point during each larval stage and peaking again in adults; sqt-1 transcripts are also detected in animals at the L1-L2d molt; in the temporally distinct waves of collagen gene expression that occur during larval development, sqt-1 mRNA appears to be synthesized during the second, or intermediate, stage, just very slightly earlier than sqt-3/col-1 and dpy-13; SQT-1 protein is detected in cuticle extracts from L2, L3, and L4 larvae, and from adults, but is not detected in extracts from L1 or dauer larvae; sqt-1 interacts genetically with a number of genes also required for normal cuticle and organismal morphology, e.g., rol-6 and lon-3, which also encode cuticular collagens. | Paper_evidence | WBPaper00000465 | |||||
| WBPaper00000906 | |||||||||
| WBPaper00001100 | |||||||||
| WBPaper00001273 | |||||||||
| WBPaper00001951 | |||||||||
| WBPaper00002512 | |||||||||
| WBPaper00003774 | |||||||||
| WBPaper00005272 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 12 Jan 2006 00:00:00 | ||||||||
| Automated_description | A structural constituent of collagen and cuticulin-based cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle. Predicted to be part of collagen trimer. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | B0491.2 | |||||||
| Corresponding_transcript | B0491.2.1 | ||||||||
| B0491.2.2 | |||||||||
| Other_sequence (32) | |||||||||
| Associated_feature | WBsf989715 | ||||||||
| WBsf989716 | |||||||||
| WBsf989717 | |||||||||
| WBsf989718 | |||||||||
| WBsf1013213 | |||||||||
| WBsf1013214 | |||||||||
| WBsf1013215 | |||||||||
| WBsf223920 | |||||||||
| WBsf223921 | |||||||||
| Experimental_info | RNAi_result (19) | ||||||||
| Expr_pattern | Expr616 | ||||||||
| Expr715 | |||||||||
| Expr1187 | |||||||||
| Expr1023819 | |||||||||
| Expr1032499 | |||||||||
| Expr1143258 | |||||||||
| Expr2016116 | |||||||||
| Expr2034351 | |||||||||
| Drives_construct | WBCnstr00035266 | ||||||||
| Construct_product | WBCnstr00035266 | ||||||||
| Antibody | WBAntibody00000250 | ||||||||
| WBAntibody00000251 | |||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (323) | |||||||||
| Interaction (298) | |||||||||
| WBProcess | WBbiopr:00000124 | ||||||||
| Map_info | Map | II | Position | 3.43991 | Error | 0.004153 | |||
| Well_ordered | |||||||||
| Positive | Inside_rearr | mnDf90 | |||||||
| Positive_clone | B0491 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||||
| C25B12 | |||||||||
| Mapping_data | 2_point (17) | ||||||||
| Multi_point | 209 | ||||||||
| 254 | |||||||||
| 292 | |||||||||
| 293 | |||||||||
| 294 | |||||||||
| 295 | |||||||||
| 296 | |||||||||
| 338 | |||||||||
| 832 | |||||||||
| 833 | |||||||||
| 834 | |||||||||
| 835 | |||||||||
| 846 | |||||||||
| 1054 | |||||||||
| 1243 | |||||||||
| 1385 | |||||||||
| 2219 | |||||||||
| 2792 | |||||||||
| 3442 | |||||||||
| 5535 | |||||||||
| 5704 | |||||||||
| 5705 | |||||||||
| Pos_neg_data (12) | |||||||||
| Landmark_gene | |||||||||
| Reference (137) | |||||||||
| Method | Gene |
