WormBase Tree Display for Gene: WBGene00001073

WBGene00001073 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: F46E10
  Identity: Version: 1
    Name: CGC_name: dpy-11 Person_evidence: WBPerson261
      Sequence_name: F46E10.9
      Molecular_name: F46E10.9
        F46E10.9.1
        CE20819
        F46E10.9.2
      Other_name: CELE_F46E10.9 Accession_evidence: NDB BX284605
      Public_name: dpy-11
    DB_info: Database: AceView gene 5G992
        WormQTL gene WBGene00001073
        WormFlux gene WBGene00001073
        NDB locus_tag CELE_F46E10.9
        Panther gene CAEEL|WormBase=WBGene00001073|UniProtKB=G5EC91
          family PTHR46107
        NCBI gene 179040
        RefSeq protein NM_001383321.2
        TREEFAM TREEFAM_ID TF106376
        TrEMBL UniProtAcc G5EC91
        UniProt_GCRP UniProtAcc G5EC91
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:22 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: dpy
    Reference_allele: WBVar00143044
    Allele (97)
    Legacy_information: e224 : medium dumpy. ES3 (adult) ES2 (larvae). ME2. NA > 10 (e33 e1180icr (these and most other alleles have much stronger dumpy ('piggy') phenotype) etc.).
      See also e33, e752, e1180, e1194, s360
      [C.elegansII] e224 : medium dumpy. ES3 (adult) ES2 (larvae). ME2. Males Ram (lumpy rays) at25C. OA>10: e33, e1180icr (these and most other alleles have much stronger dumpy or 'piggy' phenotype) etc.), e455,e733, e752, s287 (induced on eT1), s10, s261, s360fdi etc. [Brenner 1974; Baird and Emmons 1990; CB]
    Strain (139)
    RNASeq_FPKM (74)
    GO_annotation: 00011338
      00011339
      00011340
      00011341
      00011342
      00011343
      00011344
      00011345
      00011346
    Contained_in_operon: CEOP5120
    Ortholog: WBGene00052170 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00038252 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00115194 Pristionchus pacificus From_analysis: OMA
            Inparanoid_8
      WBGene00147987 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00127815 Caenorhabditis japonica From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00224407 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g1769 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g5610 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g8480 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g8737 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g5504 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g11260 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g14908 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g10696 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g10082 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g11360 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00182.g6385 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_17161.g25610 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-dpy-11 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold630.g17519 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00013.g855 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_10796 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_017940 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g00877 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g2349 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_50214510 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrV_pilon.g14452 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00242776 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00280427 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00255754 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00290222 Trichuris muris From_analysis: WormBase-Compara
      WBGene00301169 Trichuris muris From_analysis: WormBase-Compara
      FB:FBgn0034914 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-030131-2327 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-050706-155 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            Panther
      HGNC:25237 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            Panther
            PhylomeDB
      HGNC:15487 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:106558 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            Panther
      MGI:1919986 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      RGD:1305146 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            OrthoInspector
            Panther
      RGD:1308455 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
    Paralog (14)
    Structured_description: Automated_description: Enables protein-disulfide reductase activity. Involved in several processes, including cuticle development involved in collagen and cuticulin-based cuticle molting cycle; post-embryonic body morphogenesis; and protein folding. Located in endomembrane system. Expressed in several structures, including R1_hyp; R2_hyp; R3_hyp; R4_hyp; and R5_hyp. Is an ortholog of human TMX1 (thioredoxin related transmembrane protein 1). Paper_evidence: WBPaper00065943
          Curator_confirmed (2)
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F46E10.9
    Corresponding_transcript: F46E10.9.1
      F46E10.9.2
    Other_sequence (67)
    Associated_feature (20)
  Experimental_info: RNAi_result (20)
    Expr_pattern: Chronogram1745
      Expr1854
      Expr1855
      Expr6089
      Expr13275
      Expr1026593
      Expr1030681
      Expr1151367
      Expr2011056
      Expr2029293
    Drives_construct: WBCnstr00002463
      WBCnstr00010487
      WBCnstr00010488
      WBCnstr00042718
    Construct_product: WBCnstr00010488
    Microarray_results (22)
    Expression_cluster (192)
    Interaction (155)
    WBProcess: WBbiopr:00000124
  Map_info: Map: V Position: 0
    Well_ordered
    Positive: Inside_rearr: sDf20
        sDf30
        nDf1
        nDf18
        rT1
      Positive_clone: F46E10 Inferred_automatically: From sequence, transcript, pseudogene data
        T04F11
    Negative: Outside_rearr: sDf36
        eDf1
        nDf42
      Negative_clone: W01A11
    Mapping_data: 2_point (100)
      Multi_point (259)
      Pos_neg_data (15)
    Landmark_gene
  Reference (113)
  Remark: Julia Pak rescued dpy-11 with T04F11 when she was a rotation student in my lab.
    Sequence connection from [Ko F]
  Method: Gene