WormBase Tree Display for Gene: WBGene00012759
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WBGene00012759 | SMap | S_parent | Sequence | Y41C4A | |||
---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||
Name | CGC_name | sup-1 | Paper_evidence | WBPaper00041593 | |||
Person_evidence | WBPerson201 | ||||||
Sequence_name | Y41C4A.13 | ||||||
Molecular_name | Y41C4A.13 | ||||||
Y41C4A.13.1 | |||||||
CE20253 | |||||||
Other_name | CELE_Y41C4A.13 | Accession_evidence | NDB | BX284603 | |||
Public_name | sup-1 | ||||||
DB_info | Database | AceView | gene | 3M822 | |||
WormQTL | gene | WBGene00012759 | |||||
WormFlux | gene | WBGene00012759 | |||||
NDB | locus_tag | CELE_Y41C4A.13 | |||||
Panther | gene | CAEEL|WormBase=WBGene00012759|UniProtKB=Q9XWU2 | |||||
family | PTHR34149 | ||||||
NCBI | gene | 189815 | |||||
RefSeq | protein | NM_067119.7 | |||||
SwissProt | UniProtAcc | Q9XWU2 | |||||
TREEFAM | TREEFAM_ID | TF319571 | |||||
UniProt_GCRP | UniProtAcc | Q9XWU2 | |||||
Species | Caenorhabditis elegans | ||||||
History (2) | |||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | sup | ||||||
Reference_allele | WBVar00143668 | ||||||
Allele (115) | |||||||
Legacy_information | e995dm : dominant suppressor of unc-17(e245); does not suppress unc-17(e876); no phenotype alone. ES3 in presence of e245 ME3. NA > 5 (e995xri etc. : all resemble e995). | ||||||
See also e995, e996, e1826, e1827, e1909, e1955 | |||||||
[C.elegansII] e995dm : dominant allele-specific suppressor of unc-17(e245); does not suppress unc-17(e876); no phenotype alone. ES3 in presence of e245 ME3. OA>5: e996xri, e1827, e1955 etc. (all similar). [CB; RM] | |||||||
Strain | WBStrain00033410 | ||||||
WBStrain00033411 | |||||||
WBStrain00033415 | |||||||
WBStrain00033416 | |||||||
WBStrain00004371 | |||||||
WBStrain00004632 | |||||||
WBStrain00023506 | |||||||
WBStrain00023498 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (15) | |||||||
Ortholog (25) | |||||||
Paralog | WBGene00007474 | Caenorhabditis elegans | From_analysis | Panther | |||
WBGene00009915 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00010598 | Caenorhabditis elegans | From_analysis | Panther | ||||
WBGene00011220 | Caenorhabditis elegans | From_analysis | Panther | ||||
WBGene00044477 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
WBGene00194747 | Caenorhabditis elegans | From_analysis | Panther | ||||
WBGene00018348 | Caenorhabditis elegans | From_analysis | Panther | ||||
WBGene00194733 | Caenorhabditis elegans | From_analysis | Panther | ||||
WBGene00022698 | Caenorhabditis elegans | From_analysis | Panther | ||||
WBGene00044756 | Caenorhabditis elegans | From_analysis | Panther | ||||
Structured_description | Concise_description | sup-1 encodes a novel, single-pass transmembrane protein; sup-1 was identified as an allele-specific dominant suppressor of unc-17(e245); unc-17 encodes a synaptic vesicle acetylcholine transporter and the e245 missense mutation results in substitution of arginine for glycine in the ninth transmembrane domain and reduced levels of UNC-17 protein; sup-1 is defined by several alleles that all behave similarly as dominant suppressors of unc-17(e245) and have no phenotype on their own; SUP-1 reporter fusion proteins are expressed in cholinergic neurons and body wall muscles, where they localize to the plasma membrane and are found in synaptic regions. | Paper_evidence | WBPaper00004985 | |||
WBPaper00002665 | |||||||
WBPaper00041593 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 04 Dec 2012 00:00:00 | ||||||
Automated_description | Located in neuron projection; neuronal cell body membrane; and synapse. Expressed in body wall musculature; neurons; and ventral nerve cord. | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | Y41C4A.13 | |||||
Corresponding_transcript | Y41C4A.13.1 | ||||||
Other_sequence (27) | |||||||
Associated_feature | WBsf717994 | ||||||
WBsf994480 | |||||||
WBsf994481 | |||||||
WBsf1016074 | |||||||
WBsf1016075 | |||||||
WBsf227597 | |||||||
Experimental_info | RNAi_result | WBRNAi00020471 | Inferred_automatically | RNAi_primary | |||
WBRNAi00006756 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00036994 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00056355 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr10560 | ||||||
Expr1028714 | |||||||
Expr1035644 | |||||||
Expr1159840 | |||||||
Expr2017128 | |||||||
Expr2035264 | |||||||
Drives_construct | WBCnstr00015438 | ||||||
WBCnstr00015440 | |||||||
WBCnstr00015444 | |||||||
WBCnstr00015445 | |||||||
WBCnstr00015446 | |||||||
WBCnstr00015447 | |||||||
WBCnstr00015759 | |||||||
Construct_product | WBCnstr00015438 | ||||||
WBCnstr00015440 | |||||||
WBCnstr00015441 | |||||||
WBCnstr00015444 | |||||||
WBCnstr00015445 | |||||||
WBCnstr00015446 | |||||||
WBCnstr00015447 | |||||||
WBCnstr00015759 | |||||||
Microarray_results (18) | |||||||
Expression_cluster (209) | |||||||
Interaction (16) | |||||||
Map_info | Positive | Positive_clone | Y41C4A | Inferred_automatically | From sequence, transcript, pseudogene data | ||
Mapping_data | 2_point | 77 | |||||
89 | |||||||
Multi_point | 92 | ||||||
1660 | |||||||
2028 | |||||||
2029 | |||||||
Interpolated_map_position | III | 12.044 | |||||
Reference | WBPaper00037329 | ||||||
WBPaper00039285 | |||||||
WBPaper00041593 | |||||||
WBPaper00043425 | |||||||
WBPaper00058518 | |||||||
WBPaper00061353 | |||||||
Method | Gene |