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WormBase Tree Display for Gene: WBGene00000063

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Name Class

WBGene00000063SMapS_parentSequenceT04C12
IdentityVersion1
NameCGC_nameact-1Person_evidenceWBPerson259
Sequence_nameT04C12.6
Molecular_nameT04C12.6
T04C12.6.1
CE13148
Other_nameCELE_T04C12.6Accession_evidenceNDBBX284605
Public_nameact-1
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:19WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classact
Allele (13)
StrainWBStrain00033488
In_clusteract-123
RNASeq_FPKM (74)
GO_annotation (17)
OrthologWBGene00025260Caenorhabditis briggsaeFrom_analysisOrthoMCL
WBGene00025261Caenorhabditis briggsaeFrom_analysisOrthoMCL
WBGene00025265Caenorhabditis briggsaeFrom_analysisOrthoMCL
WBGene00025266Caenorhabditis briggsaeFrom_analysisOrthoMCL
WBGene00037707Caenorhabditis briggsaeFrom_analysisOrthoMCL
WBGene00041507Caenorhabditis briggsaeFrom_analysis (2)
WBGene00041508Caenorhabditis briggsaeFrom_analysisOrthoMCL
WBGene00042553Caenorhabditis briggsaeFrom_analysisOrthoMCL
WBGene00066197Caenorhabditis remaneiFrom_analysis (3)
WBGene00132986Caenorhabditis japonicaFrom_analysisTreeFam
WBGene00195125Caenorhabditis brenneriFrom_analysisInparanoid_8
WBGene00183122Caenorhabditis japonicaFrom_analysisInparanoid_8
WBGene00098673Pristionchus pacificusFrom_analysis (2)
WBGene00225347Brugia malayiFrom_analysisWormBase-Compara
WBGene00228785Brugia malayiFrom_analysisWormBase-Compara
WBGene00229498Brugia malayiFrom_analysisWormBase-Compara
WBGene00229499Brugia malayiFrom_analysisWormBase-Compara
CSP21.g3544Caenorhabditis parvicaudaFrom_analysisWormBase-Compara
CSP31.g1121Caenorhabditis uteleiaFrom_analysisWormBase-Compara
CSP38.g15217Caenorhabditis quiockensisFrom_analysisWormBase-Compara
GCK72_016607Caenorhabditis remaneiFrom_analysisWormBase-Compara
chrV_pilon.g15681Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00239553Onchocerca volvulusFrom_analysisWormBase-Compara
WBGene00239554Onchocerca volvulusFrom_analysisWormBase-Compara
WBGene00272225Pristionchus pacificusFrom_analysisWormBase-Compara
WBGene00276137Pristionchus pacificusFrom_analysisWormBase-Compara
WBGene00258064Strongyloides rattiFrom_analysisWormBase-Compara
WBGene00261913Strongyloides rattiFrom_analysisWormBase-Compara
WBGene00264369Strongyloides rattiFrom_analysisWormBase-Compara
WBGene00288575Trichuris murisFrom_analysisWormBase-Compara
SGD:S000001855Saccharomyces cerevisiaeFrom_analysis (9)
FB:FBgn0000042Drosophila melanogasterFrom_analysis (7)
FB:FBgn0000043Drosophila melanogasterFrom_analysis (6)
FB:FBgn0000044Drosophila melanogasterFrom_analysis (3)
FB:FBgn0000045Drosophila melanogasterFrom_analysis (3)
FB:FBgn0000047Drosophila melanogasterFrom_analysis (3)
FB:FBgn0000046Drosophila melanogasterFrom_analysis (3)
ZFIN:ZDB-GENE-000329-1Danio rerioFrom_analysis (8)
ZFIN:ZDB-GENE-000329-3Danio rerioFrom_analysis (8)
HGNC:132Homo sapiensFrom_analysis (8)
HGNC:144Homo sapiensFrom_analysis (7)
MGI:87904Mus musculusFrom_analysis (8)
MGI:87906Mus musculusFrom_analysis (7)
RGD:628837Rattus norvegicusFrom_analysis (8)
RGD:1304556Rattus norvegicusFrom_analysis (7)
RGD:2320108Rattus norvegicusFrom_analysis (7)
Paralog (11)
Structured_descriptionConcise_descriptionact-1 encodes an actin isoform that is required for proper body wall muscle and pharyngeal muscle structures and the motility of animals; actins have highly similar amino acid sequences; ACT-1 is identical to ACT-3; act-1 functions redundantly with two other actin isoforms, act-2 and act-3, to control cytoplasmic microfilament function in the early embryo.Paper_evidenceWBPaper00001178
WBPaper00014413
WBPaper00027028
Curator_confirmedWBPerson324
Date_last_updated29 Mar 2007 00:00:00
Automated_descriptionPredicted to be a structural constituent of cytoskeleton. Involved in cortical actin cytoskeleton organization; embryo development; and mitotic cytokinesis. Located in striated muscle thin filament. Expressed in body wall musculature and gonad. Human ortholog(s) of this gene implicated in several diseases, including Baraitser-Winter syndrome 1; Baraitser-Winter syndrome 2; and autosomal dominant nonsyndromic deafness 20. Is an ortholog of human ACTB (actin beta).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:1588Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:132)
DOID:0081113Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:144)
DOID:10881Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:132)
DOID:0081112Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:132)
DOID:0110550Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:144)
Molecular_infoCorresponding_CDST04C12.6
Corresponding_transcriptT04C12.6.1
Other_sequence (456)
Associated_featureWBsf647226
WBsf647227
WBsf661678
WBsf661679
WBsf1001264
WBsf1001265
WBsf1020400
WBsf232452
WBsf232453
WBsf232454
Experimental_infoRNAi_result (55)
Expr_patternExpr558
Expr2793
Expr4555
Expr9252
Expr1030024
Expr1156000
Expr2009221
Expr2027458
Drives_constructWBCnstr00006031
WBCnstr00006032
WBCnstr00013852
WBCnstr00037760
Construct_productWBCnstr00015675
WBCnstr00015678
WBCnstr00037760
WBCnstr00038658
AntibodyWBAntibody00001783
Microarray_resultsSMD_T04C12.6
GPL19516_CGZ0033111
GPL19516_CGZ0033112
GPL19516_CGZ0033113
GPL19516_CGZ0033114
GPL21109_T04C12.6.1
GPL8304_CE_WBGene00000063_B
GPL9450_T04C12.6
cea2.c.38095
Expression_cluster (171)
Interaction (326)
WBProcessWBbiopr:00000096
Map_infoMapVPosition2.94475Error0.000513
PositivePositive_cloneT04C12Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (106)
RemarkT04C12.4 changed to T04C12.6. email from JAH 0109
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene