WormBase Tree Display for Gene: WBGene00001580

WBGene00001580 SMap: S_parent: Sequence: CHROMOSOME_IV
  Identity: Version: 1
    Name (5)
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:25 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: gex
    Allele (48)
    Strain: WBStrain00040419
      WBStrain00024269
      WBStrain00051117
      WBStrain00055525
    RNASeq_FPKM (74)
    GO_annotation (26)
    Ortholog: WBGene00071914 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00026209 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00190818 Caenorhabditis brenneri From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00119948 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00223935 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g11615 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g2348 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g5351 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g11088 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g7786 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g15787 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g4609 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g4498 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g14562 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP39.g16051 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP39.g21063 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP39.g26169 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g22711 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00588.g12536 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_00588.g12537 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_01475.g16452 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-gex-3 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold629.g12693 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp11.Scaffold629.g12694 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_01712.g22672 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_04810 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_014301 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g03122 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g10769 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_40243210 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIV_pilon.g12067 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00242588 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00095985 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00262698 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00286590 Trichuris muris From_analysis: WormBase-Compara
      FB:FBgn0011771 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-080204-117 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-030131-4426 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:4862 Homo sapiens From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:7666 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1355333 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1926063 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:61939 Rattus norvegicus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1312032 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Structured_description: Concise_description: The gex-3 gene encodes a homolog of NAP1/NCKAP1, a mammalian protein ligand of the small GTPase Rac1, and of Drosophila HEM2/NAP1/KETTE; gex-3 is required for tissue morphogenesis and cell migrations; in gex-3 mutants, cells differentiate properly but fail to become organized. Paper_evidence: WBPaper00005149
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Involved in several processes, including egg-laying behavior; embryonic morphogenesis; and positive regulation of cellular component organization. Located in cell junction. Part of SCAR complex. Expressed in intestinal cell. Human ortholog(s) of this gene implicated in immunodeficiency 72. Is an ortholog of human NCKAP1 (NCK associated protein 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0112015 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4862)
  Molecular_info: Corresponding_CDS: F28D1.10
    Corresponding_transcript: F28D1.10.1
    Other_sequence (40)
    Associated_feature: WBsf646473
      WBsf229287
      WBsf229288
  Experimental_info: RNAi_result (41)
    Expr_pattern: Expr1828
      Expr8395
      Expr10794
      Expr12485
      Expr1017668
      Expr1030946
      Expr1149732
      Expr2012024
      Expr2030260
    Drives_construct: WBCnstr00013296
      WBCnstr00036848
    Construct_product: WBCnstr00009364
      WBCnstr00013296
      WBCnstr00017546
      WBCnstr00036848
    Antibody: WBAntibody00000464
    Microarray_results (22)
    Expression_cluster (120)
    Interaction (100)
  Map_info: Positive: Positive_clone: F28D1 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4816
    Interpolated_map_position: IV 5.91283
  Reference (37)
  Remark: most on F28D1.10; the 3' end on F08G5 (nucleotides 1 to 4576). predicted gene previously called CeHEM2; mammalian homolog is called HEM2 and NAP1, and the fly homolog is called KETTE. [Soto M]
  Method: Gene