Predicted to enable ATP-dependent activity, acting on DNA. Predicted to be involved in transcription-coupled nucleotide-excision repair. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in several diseases, including Cockayne syndrome (multiple); gastrointestinal system cancer (multiple); and respiratory system cancer (multiple). Is an ortholog of human ERCC6 (ERCC excision repair 6, chromatin remodeling factor).