grld-1 is orthologous to human RBM15 (OMIM:606077, mutated in infantile acute megakaryoblastic leukemia) and Drosophila NITO; GRLD-1 encodes a paralog of DIN-1; like DIN-1, it has N-terminal RNA recognition motifs (RRMs) and a C-terminal SID/RD (SMRT interaction domain/repressor) domain.
Predicted to enable RNA binding activity. Located in nucleus. Expressed in epithelial cell; lateral ganglion; muscle cell; and neurons. Is an ortholog of human RBM15 (RNA binding motif protein 15) and RBM15B (RNA binding motif protein 15B).
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.