WormBase Tree Display for Gene: RGD:2351
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| RGD:2351 | Identity | Name | CGC_name | Chrnb4 | Inferred_automatically | AGR_import |
|---|---|---|---|---|---|---|
| Public_name | Chrnb4 | |||||
| DB_info | Database | RGD | id | 2351 | ||
| AGR | cURI | RGD:2351 | ||||
| EnsEMBL | ENSEMBL_geneID | ENSRNOG00000014427 | ||||
| UniProt | UniProt_AC | P12392 | ||||
| Species | Rattus norvegicus | |||||
| Status | Live | |||||
| Gene_info | Biotype | SO:0001217 | ||||
| Ortholog | WBGene00000047 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | ||
| OrthoFinder | ||||||
| PhylomeDB | ||||||
| Structured_description | Automated_description | Enables acetylcholine binding activity and heterocyclic compound binding activity. Predicted to be involved in positive regulation of transmission of nerve impulse and signal transduction. Predicted to act upstream of or within several processes, including behavioral response to nicotine; chemical synaptic transmission; and neuronal action potential. Located in plasma membrane. Part of acetylcholine-gated channel complex. Biomarker of depressive disorder. Human ortholog(s) of this gene implicated in cocaine abuse; lung cancer (multiple); and oral cavity cancer. Orthologous to human CHRNB4 (cholinergic receptor nicotinic beta 4 subunit); PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; INTERACTS WITH (S)-anabasine; (S)-nicotine; 17beta-estradiol. | Inferred_automatically | AGR_import |
