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WormBase Tree Display for Gene: RGD:620325

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Name Class

RGD:620325IdentityNameCGC_namePcsk4Inferred_automaticallyAGR_import
Public_namePcsk4
DB_infoDatabaseRGDid620325
AGRcURIRGD:620325
EnsEMBLENSEMBL_geneIDENSRNOG00000016405
UniProtUniProt_ACQ78EH2
SpeciesRattus norvegicus
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00002232Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Hieranoid
Inparanoid
OrthoFinder
Panther
SonicParanoid
Structured_descriptionAutomated_descriptionPredicted to enable serine-type endopeptidase activity. Predicted to be involved in several processes, including acrosome reaction; binding activity of sperm to zona pellucida; and sperm capacitation. Predicted to be located in acrosomal membrane. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma. Orthologous to human PCSK4 (proprotein convertase subtilisin/kexin type 4); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,2',5,5'-tetrachlorobiphenyl; 2,4-dinitrotoluene.Inferred_automaticallyAGR_import