NMK. Encodes homeoprotein most similar to Drosophila empty spiracles and Distal-less. ceh-23:lacZ expressed primarily in amphid sensilla, CAN cells.[Wang et al. 1993; TB]
[C.elegansII] NMK. Encodes homeoprotein most similar to Drosophila empty spiracles and Distal-less. ceh-23:lacZ expressed primarily in amphid sensilla, CAN cells. [Wang et al. 1993; TB]
ceh-23 encodes a homeodomain protein required for a specific differentiated trait of the thermosensory interneuron AIY; a ceh-23::gfp promoter fusion is expressed in nine pairs of head neurons, including seven amphid sensory neurons, the BAG sensory neurons, AIY interneurons, and the CAN neurons that are in close association with the excretory canal.
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in determination of adult lifespan; neuron differentiation; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in intestine; nervous system; and tail.
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.