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WormBase Tree Display for Gene: WBGene00001954

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Name Class

WBGene00001954EvidenceCGC_data_submission
SMapS_parentSequenceZK682
IdentityVersion3
NameCGC_namehlh-10Person_evidenceWBPerson346
Sequence_nameZK682.4
Molecular_nameZK682.4
ZK682.4.1
CE47615
Other_nameCeABF-1
CELE_ZK682.4Accession_evidenceNDBBX284605
Public_namehlh-10
DB_infoDatabaseAceViewgene5J758
WormQTLgeneWBGene00001954
WormFluxgeneWBGene00001954
NDBlocus_tagCELE_ZK682.4
PanthergeneCAEEL|WormBase=WBGene00001954|UniProtKB=Q23579
familyPTHR23349
NCBIgene191402
RefSeqproteinNM_073000.4
SwissProtUniProtAccQ23579
UniProt_GCRPUniProtAccQ23579
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:26WBPerson1971EventImportedInitial conversion from geneace
311 Mar 2021 09:37:10WBPerson1983Name_changeOther_nameCeABF-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classhlh
Allele (27)
StrainWBStrain00002261
WBStrain00031463
RNASeq_FPKM (74)
GO_annotation (15)
Ortholog (32)
ParalogWBGene00001953Caenorhabditis elegansFrom_analysisPanther
WBGene00001962Caenorhabditis elegansFrom_analysisPanther
WBGene00001957Caenorhabditis elegansFrom_analysisPanther
WBGene00001981Caenorhabditis elegansFrom_analysisPanther
WBGene00001956Caenorhabditis elegansFrom_analysisPanther
Structured_descriptionAutomated_descriptionEnables protein heterodimerization activity and transcription corepressor activity. Involved in negative regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Expressed in ADLL; ADLR; ASEL; ASER; and neurons. Human ortholog(s) of this gene implicated in coronary artery disease and ventricular septal defect. Is an ortholog of human MSC (musculin) and TCF21 (transcription factor 21).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:1657Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11632)
DOID:3393Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11632)
Molecular_infoCorresponding_CDSZK682.4
Corresponding_CDS_historyZK682.4:wp231
Corresponding_transcriptZK682.4.1
Other_sequenceCJC01351_1
Associated_featureWBsf652900
WBsf652901
WBsf978808
WBsf1000852
WBsf1000853
WBsf1000854
WBsf1020148
Transcription_factorWBTranscriptionFactor000067
WBTranscriptionFactor000077
Experimental_infoRNAi_resultWBRNAi00038417Inferred_automaticallyRNAi_primary
WBRNAi00059660Inferred_automaticallyRNAi_primary
WBRNAi00022129Inferred_automaticallyRNAi_primary
Expr_patternChronogram385
Expr1673
Expr2960
Expr7899
Expr14595
Expr1011155
Expr1163072
Expr2012490
Expr2030729
Drives_constructWBCnstr00004463
WBCnstr00011045
WBCnstr00012976
WBCnstr00036564
WBCnstr00041175
Construct_productWBCnstr00016001
WBCnstr00036564
Microarray_results (17)
Expression_cluster (56)
Interaction (25)
Map_infoMapVPosition1.974Error0.002284
PositivePositive_cloneZK682Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4405
5401
5405
Pseudo_map_position
Reference (9)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene