WormBase Tree Display for Gene: WBGene00004273
expand all nodes | collapse all nodes | view schema
| WBGene00004273 | SMap | S_parent | Sequence | T23H2 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | rab-10 | Paper_evidence | WBPaper00027018 | |||||
| Person_evidence | WBPerson451 | ||||||||
| Sequence_name | T23H2.5 | ||||||||
| Molecular_name | T23H2.5 | ||||||||
| T23H2.5.1 | |||||||||
| CE14114 | |||||||||
| Other_name | gum-1 | Person_evidence | WBPerson352 | ||||||
| CELE_T23H2.5 | Accession_evidence | NDB | BX284601 | ||||||
| Public_name | rab-10 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:34 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 23 Mar 2006 16:37:22 | WBPerson2970 | Event | Acquires_merge | WBGene00001797 | ||||
| Name_change | Other_name | gum-1 | |||||||
| Acquires_merge | WBGene00001797 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | rab | ||||||||
| Allele (22) | |||||||||
| Legacy_information | [C.elegansII] q373 : accumulates large, possibly aqueous vesicles in gut, leading to marbled appearance under Nomarski. OA2: dx2ts, oz162. [EJ] | ||||||||
| Strain | WBStrain00033464 | ||||||||
| WBStrain00033465 | |||||||||
| WBStrain00036258 | |||||||||
| WBStrain00004454 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (52) | |||||||||
| Ortholog (42) | |||||||||
| Paralog (32) | |||||||||
| Structured_description | Concise_description | rab-10 encodes a Rab-like GTPase that is a member of the Ras superfamily of small GTPases; RAB-10 is required, upstream of RME-1, for basolateral endocytic recycling in the intestine, but not in oocytes or coelomocytes; RAB-10 is also required for GLR-1 receptor recycling in interneurons; a RAB-10::GFP fusion protein is widely expressed and in the intestine, localizes to early endosomes and the Golgi. | Paper_evidence | WBPaper00027018 | |||||
| WBPaper00030925 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 29 Jun 2010 00:00:00 | ||||||||
| Automated_description | Enables GTPase activating protein binding activity and ankyrin repeat binding activity. Involved in several processes, including negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process; receptor recycling; and vesicle-mediated transport. Located in several cellular components, including Golgi medial cisterna; cholinergic synapse; and cytoplasmic vesicle. Expressed in several structures, including PVD; coelomocyte; hermaphrodite gonad; hypodermis; and somatic nervous system. Is an ortholog of human RAB10 (RAB10, member RAS oncogene family). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | T23H2.5 | |||||||
| Corresponding_transcript | T23H2.5.1 | ||||||||
| Other_sequence (78) | |||||||||
| Associated_feature | WBsf976737 | ||||||||
| WBsf976738 | |||||||||
| WBsf976739 | |||||||||
| WBsf976740 | |||||||||
| WBsf976741 | |||||||||
| WBsf976742 | |||||||||
| WBsf976743 | |||||||||
| WBsf219586 | |||||||||
| WBsf219587 | |||||||||
| Experimental_info | RNAi_result (41) | ||||||||
| Expr_pattern | Expr3585 | ||||||||
| Expr3825 | |||||||||
| Expr8330 | |||||||||
| Expr11666 | |||||||||
| Expr12468 | |||||||||
| Expr1020885 | |||||||||
| Expr1032112 | |||||||||
| Expr1157535 | |||||||||
| Expr2015213 | |||||||||
| Expr2033447 | |||||||||
| Drives_construct | WBCnstr00001800 | ||||||||
| WBCnstr00001804 | |||||||||
| WBCnstr00007960 | |||||||||
| WBCnstr00035595 | |||||||||
| Construct_product (17) | |||||||||
| Microarray_results (23) | |||||||||
| Expression_cluster (103) | |||||||||
| Interaction (71) | |||||||||
| Map_info | Map | I | Position | 1.11939 | |||||
| Positive | Positive_clone | T23H2 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 5563 | |||||||
| 4681 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (66) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| [200811 gw3] Modified Map position as it was a reverse physical that could not be fixed by automated methods. (1.10072) | |||||||||
| Method | Gene |
