WormBase Tree Display for Gene: WBGene00009176
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| WBGene00009176 | SMap | S_parent | Sequence | F26H9 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | nmat-2 | Person_evidence | WBPerson2335 | |||||
| Sequence_name | F26H9.4 | ||||||||
| Molecular_name | F26H9.4 | ||||||||
| F26H9.4.1 | |||||||||
| CE09709 | |||||||||
| Other_name | CELE_F26H9.4 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | nmat-2 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:49 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 11 May 2012 16:05:19 | WBPerson2970 | Name_change | CGC_name | nmat-2 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | nmat | ||||||||
| Allele (21) | |||||||||
| Strain | WBStrain00054701 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (19) | |||||||||
| Ortholog (44) | |||||||||
| Paralog | WBGene00012295 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | F26H9.4 encodes a nicotinamide mononucleotide adenylyl transferase; by homology, F26H9.4 is predicted to function in energy metabolism by catalyzing the formation of NAD from nicotinamide mononucleotide and AMP or the formation of NaNAD from nicotinic acid adenine dinucleotide and AMP; in C. elegans, F26H9.4 expression is enriched in the germline; F26H9.4 is most closely related to the mammalian Nmnat3 proteins which localize to mitochondria. | Paper_evidence | WBPaper00040537 | |||||
| WBPaper00006390 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 21 Dec 2011 00:00:00 | ||||||||
| Automated_description | Predicted to enable nicotinamide-nucleotide adenylyltransferase activity and nicotinate-nucleotide adenylyltransferase activity. Predicted to be involved in NAD biosynthetic process. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 9 and spondyloepiphyseal dysplasia, sensorineural hearing loss, intellectual developmental disorder, and Leber congenital amaurosis. Is an ortholog of human NMNAT1 (nicotinamide nucleotide adenylyltransferase 1) and NMNAT3 (nicotinamide nucleotide adenylyltransferase 3). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0110005 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:17877) | ||||
| DOID:0112290 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:17877) | ||||||
| Molecular_info | Corresponding_CDS | F26H9.4 | |||||||
| Corresponding_transcript | F26H9.4.1 | ||||||||
| Associated_feature | WBsf984648 | ||||||||
| WBsf1010348 | |||||||||
| WBsf220068 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00031477 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00116933 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00007747 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00023443 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00045707 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00003491 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00077832 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr10700 | ||||||||
| Expr1012235 | |||||||||
| Expr1034002 | |||||||||
| Expr1149619 | |||||||||
| Expr2014330 | |||||||||
| Expr2032571 | |||||||||
| Drives_construct | WBCnstr00017474 | ||||||||
| WBCnstr00032398 | |||||||||
| Construct_product | WBCnstr00015825 | ||||||||
| WBCnstr00017474 | |||||||||
| WBCnstr00022608 | |||||||||
| WBCnstr00032398 | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (110) | |||||||||
| Interaction (47) | |||||||||
| Map_info | Map | I | Position | 3.7343 | |||||
| Positive | Positive_clone | F26H9 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00040537 | |||||||||
| WBPaper00043679 | |||||||||
| WBPaper00047711 | |||||||||
| WBPaper00049307 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00055785 | |||||||||
| WBPaper00064339 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
