WormBase Tree Display for Gene: WBGene00012929
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| WBGene00012929 | SMap | S_parent | Sequence | Y47D3A | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | rsks-1 | Person_evidence | WBPerson555 | |||||
| Sequence_name | Y47D3A.16 | ||||||||
| Molecular_name | Y47D3A.16 | ||||||||
| Y47D3A.16.1 | |||||||||
| CE46969 | |||||||||
| Other_name | S6K | Paper_evidence | WBPaper00035954 | ||||||
| CELE_Y47D3A.16 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | rsks-1 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:54 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 01 Apr 2005 11:05:24 | WBPerson2970 | Name_change | CGC_name | rsks-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | rsks | ||||||||
| Allele (147) | |||||||||
| Strain | WBStrain00031907 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (27) | |||||||||
| Contained_in_operon | CEOP3825 | ||||||||
| Ortholog (40) | |||||||||
| Paralog | WBGene00008311 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00011352 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00044281 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00017898 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | rsks-1 encodes a putative ribosomal protein S6 kinase (S6K) requiredadditively with IFG-1 for normally high levels of protein synthesis, andfor normally short lifespan; RSKS-1's effect on lifespan is independentof DAF-16, ISP-1, and SIR-2.1, and does not correlate with jugloneresistance, but does correlate with abnormally high resistance tostarvation and (perhaps) thermotolerance; RSKS-1 is required for normaljuglone resistance, as well as normally rapid growth and normal broodsizes; RSKS-1 is expressed in E-lineage embryonic cells, and inpharyngeal and hypodermal cells of larvae and adults; RSKS-1 isorthologous to human RPS6KB1 (OMIM:608938) and RPS6KB2 (OMIM:608939). | Paper_evidence | WBPaper00029007 | |||||
| WBPaper00029008 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 19 May 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable protein serine/threonine kinase activity. Involved in determination of adult lifespan; nematode larval development; and positive regulation of metabolic process. Predicted to be located in cytoplasm and nucleoplasm. Expressed in several structures, including Eala; Ealaa; Ealp; Earaa; and Earp. Is an ortholog of human RPS6KB2 (ribosomal protein S6 kinase B2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | Y47D3A.16 | |||||||
| Corresponding_CDS_history | Y47D3A.16:wp229 | ||||||||
| Corresponding_transcript | Y47D3A.16.1 | ||||||||
| Other_sequence (56) | |||||||||
| Associated_feature (16) | |||||||||
| Experimental_info | RNAi_result (39) | ||||||||
| Expr_pattern | Expr158 | ||||||||
| Expr11492 | |||||||||
| Expr15256 | |||||||||
| Expr15306 | |||||||||
| Expr1016477 | |||||||||
| Expr1035726 | |||||||||
| Expr1160202 | |||||||||
| Expr2015557 | |||||||||
| Expr2033792 | |||||||||
| Drives_construct | WBCnstr00009811 | ||||||||
| WBCnstr00042142 | |||||||||
| Construct_product | WBCnstr00009809 | ||||||||
| WBCnstr00009810 | |||||||||
| WBCnstr00009811 | |||||||||
| WBCnstr00018928 | |||||||||
| WBCnstr00019351 | |||||||||
| WBCnstr00019352 | |||||||||
| WBCnstr00019353 | |||||||||
| WBCnstr00041278 | |||||||||
| Regulate_expr_cluster | WBPaper00044638:daf-2(e1370)rsks-1(ok1255)_regulated | ||||||||
| WBPaper00049290:rsks-1(sv31)_downregulated | |||||||||
| WBPaper00049290:rsks-1(sv31)_upregulated | |||||||||
| WBPaper00057083:daf-2(e1370)rsks-1(ok1255)_post-transcriptional_downregulated | |||||||||
| WBPaper00057083:daf-2(e1370)rsks-1(ok1255)_post-transcriptional_upregulated | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (102) | |||||||||
| Interaction (88) | |||||||||
| Anatomy_function | WBbtf0646 | ||||||||
| WBbtf0647 | |||||||||
| WBbtf0648 | |||||||||
| WBbtf0649 | |||||||||
| WBProcess | WBbiopr:00000001 | ||||||||
| Map_info | Map | III | Position | 8.10036 | Error | 0.063198 | |||
| Positive | Positive_clone | Y47D3A | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5138 | |||||||
| 5306 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (82) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
