WormBase Tree Display for Gene: WBGene00019282
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| WBGene00019282 | SMap | S_parent | Sequence | K01A2 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | mps-2 | Person_evidence | WBPerson3192 | |||||
| Sequence_name | K01A2.8 | ||||||||
| Molecular_name (11) | |||||||||
| Other_name | CELE_K01A2.8 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | mps-2 | ||||||||
| DB_info | Database | AceView | gene | 2A600 | |||||
| WormQTL | gene | WBGene00019282 | |||||||
| WormFlux | gene | WBGene00019282 | |||||||
| NDB | locus_tag | CELE_K01A2.8 | |||||||
| NCBI | gene | 173419 | |||||||
| RefSeq | protein | NM_001038246.6 | |||||||
| NM_001392992.1 | |||||||||
| NM_001392991.1 | |||||||||
| TREEFAM | TREEFAM_ID | TF319130 | |||||||
| TrEMBL | UniProtAcc | Q56VR9 | |||||||
| Q86S20 | |||||||||
| Q9TZ55 | |||||||||
| UniProt_GCRP | UniProtAcc | Q56VR9 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:01 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 06 Jul 2005 10:38:45 | WBPerson2970 | Name_change | CGC_name | mps-2 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | mps | ||||||||
| Allele (84) | |||||||||
| Strain | WBStrain00032129 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00081154 | ||||||||
| 00081155 | |||||||||
| 00081156 | |||||||||
| 00081157 | |||||||||
| 00081158 | |||||||||
| 00081159 | |||||||||
| 00081160 | |||||||||
| Ortholog (13) | |||||||||
| Paralog | WBGene00019278 | ||||||||
| WBGene00019279 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| WormBase-Compara | |||||||||
| WBGene00019283 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| WormBase-Compara | |||||||||
| WBGene00086561 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Inparanoid_8 | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | mps-2 encodes single-pass transmembrane proteins that are related to the vertebrate KCNE proteins, also known as MinK-related peptides (MiRPs) that associate with, and regulate, pore-forming ion channels; mps-1 is required for the normal function of several neurons and thus for normal body touch sensation, chemotaxis to select molecules, osmotic avoidance, and nose-touch; when coexpressed in tissue culture cells with C. elegans KVS-1, MPS-2 is able to alter the activity of this potassium-selective channel, suggesting that MPS-2 functions in vivo to regulate KVS-1 activity in neurons in which the two proteins are coexpressed; in addition, activity of MPS-2, MPS-3, and KVS-1 coexpressed in culture suggests that these three proteins can form a functional ternary complex that genetic analyses indicate likely plays a role in regulating responsiveness to sodium; MPS-2 reporter fusions are expressed in the ADF amphid sensory neuron and in the enteric muscle. | Paper_evidence | WBPaper00025063 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 11 May 2007 00:00:00 | ||||||||
| Automated_description | Enables potassium channel regulator activity. Involved in regulation of chemotaxis and regulation of potassium ion transport. Predicted to be located in membrane. Expressed in several structures, including body wall musculature; enteric muscle; intestine; lateral ganglion; and rectal muscle. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | K01A2.8a | |||||||
| K01A2.8c | |||||||||
| K01A2.8d | |||||||||
| Corresponding_CDS_history | K01A2.8b:wp141 | ||||||||
| Corresponding_transcript | K01A2.8a.1 | ||||||||
| K01A2.8c.1 | |||||||||
| K01A2.8c.2 | |||||||||
| K01A2.8c.3 | |||||||||
| K01A2.8d.1 | |||||||||
| Associated_feature | WBsf649814 | ||||||||
| WBsf649815 | |||||||||
| WBsf649816 | |||||||||
| WBsf665307 | |||||||||
| WBsf665308 | |||||||||
| WBsf665309 | |||||||||
| WBsf986380 | |||||||||
| WBsf222586 | |||||||||
| WBsf222587 | |||||||||
| WBsf222588 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00085206 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00049592 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00085213 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00016375 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00033808 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00085212 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00016374 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr3266 | ||||||||
| Expr15542 | |||||||||
| Expr1017883 | |||||||||
| Expr1038334 | |||||||||
| Expr1153321 | |||||||||
| Expr2013672 | |||||||||
| Expr2031906 | |||||||||
| Drives_construct | WBCnstr00011269 | ||||||||
| WBCnstr00025948 | |||||||||
| WBCnstr00042393 | |||||||||
| Construct_product | WBCnstr00011269 | ||||||||
| WBCnstr00025948 | |||||||||
| WBCnstr00042393 | |||||||||
| Microarray_results (40) | |||||||||
| Expression_cluster (228) | |||||||||
| Interaction | WBInteraction000540646 | ||||||||
| WBInteraction000555998 | |||||||||
| WBInteraction000571277 | |||||||||
| WBInteraction000571279 | |||||||||
| WBInteraction000571282 | |||||||||
| WBInteraction000571283 | |||||||||
| WBInteraction000571285 | |||||||||
| Map_info | Map | II | Position | -15.629 | Error | 0.001668 | |||
| Positive | Positive_clone | K01A2 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5512 | |||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00025063 | ||||||||
| WBPaper00028450 | |||||||||
| WBPaper00052591 | |||||||||
| WBPaper00058272 | |||||||||
| WBPaper00060702 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
