WormBase Tree Display for Gene: WBGene00019698
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| WBGene00019698 | SMap | S_parent | Sequence | M01B12 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | riok-1 | Person_evidence | WBPerson2149 | |||||
| Sequence_name | M01B12.5 | ||||||||
| Molecular_name | M01B12.5a | ||||||||
| M01B12.5a.1 | |||||||||
| CE30555 | |||||||||
| M01B12.5a.2 | |||||||||
| M01B12.5b | |||||||||
| Other_name | M01B12.a | Curator_confirmed | WBPerson1983 | ||||||
| Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
| M01B12.b | Curator_confirmed | WBPerson1983 | |||||||
| Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
| susi-3 | Person_evidence | WBPerson6615 | |||||||
| CELE_M01B12.5 | Accession_evidence | NDB | BX284601 | ||||||
| Public_name | riok-1 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:02 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 30 Mar 2009 16:48:10 | WBPerson9133 | Name_change | CGC_name | riok-1 | ||||
| 3 | 02 Jul 2019 16:44:46 | WBPerson1983 | Name_change | Other_name | susi-3 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | riok | ||||||||
| Allele (327) | |||||||||
| Strain | WBStrain00037491 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (28) | |||||||||
| Contained_in_operon | CEOP1084 | ||||||||
| Ortholog (41) | |||||||||
| Paralog | WBGene00014012 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00013688 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | riok-1 encodes, by alternative splicing, two isoforms of a putative RIO kinase required for viability, fertility, endocytosis, and fat storage; RIOK-1 was identified as a negative regulator of endo-siRNA generation in C. elegans by a clonal screen (suppressor of siRNA gene 3, susi-3); RIOK-1 is orthologous to human RIOK1; the sterile phenotype of riok-1(RNAi) is specifically enhanced by lin-35(n2239), indicating that RIOK-1 and LIN-35 may interact in vivo; in eri-1(mg366);GFP::NRDE-3 worms, the mutated susi-3 could redistribute NRDE-3 from the cytoplasm to the nucleus. | Paper_evidence | WBPaper00004402 | |||||
| WBPaper00005655 | |||||||||
| WBPaper00006395 | |||||||||
| WBPaper00024497 | |||||||||
| WBPaper00025054 | |||||||||
| WBPaper00029258 | |||||||||
| WBPaper00030951 | |||||||||
| WBPaper00057242 | |||||||||
| Person_evidence | WBPerson28639 | ||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 29 Aug 2019 00:00:00 | ||||||||
| Automated_description | Predicted to enable protein serine/threonine kinase activity. Involved in several processes, including gamete generation; positive regulation of vulval development; and regulation of intracellular signal transduction. Predicted to be located in cytosol. Predicted to be part of preribosome, small subunit precursor. Expressed in gonad; nervous system; and vulva. Is an ortholog of human RIOK1 (RIO kinase 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | M01B12.5a | |||||||
| Corresponding_CDS_history | M01B12.5a:wp156 | ||||||||
| M01B12.5b:wp245 | |||||||||
| Corresponding_transcript | M01B12.5b | ||||||||
| M01B12.5a.1 | |||||||||
| M01B12.5a.2 | |||||||||
| Other_sequence (62) | |||||||||
| Associated_feature (13) | |||||||||
| Experimental_info | RNAi_result (37) | ||||||||
| Expr_pattern | Expr11860 | ||||||||
| Expr1021317 | |||||||||
| Expr1038509 | |||||||||
| Expr1154420 | |||||||||
| Expr2015361 | |||||||||
| Expr2033595 | |||||||||
| Drives_construct | WBCnstr00019674 | ||||||||
| WBCnstr00020410 | |||||||||
| Microarray_results (27) | |||||||||
| Expression_cluster (93) | |||||||||
| Interaction (42) | |||||||||
| Map_info | Map | I | Position | -4.48576 | Error | 0.003734 | |||
| Positive | Positive_clone | M01B12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (11) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
