WormBase Tree Display for Gene: WBGene00019983
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WBGene00019983 | SMap | S_parent | Sequence | R09E12 | ||
---|---|---|---|---|---|---|
Identity (6) | ||||||
Gene_info | Biotype | SO:0001217 | ||||
Gene_class | sti | |||||
Allele (38) | ||||||
Strain | WBStrain00001706 | |||||
WBStrain00037408 | ||||||
RNASeq_FPKM (74) | ||||||
GO_annotation (13) | ||||||
Ortholog (37) | ||||||
Paralog | WBGene00000500 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||
WBGene00006781 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||
WBGene00015916 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||
WBGene00016375 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||
WBGene00019893 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||
Structured_description | Concise_description | sti-1 encodes the C. elegans ortholog of the Sti1/Hop family of heat shock cochaperones; sti-1 plays a role in stress response, as sti-1 mutant animals have a shortened lifespan, decreased fertility at 20C, 25C, and 30C, and decreased thermotolerance; genetic interaction studies suggest that sti-1 may function together with daf-16 in regulating thermotolerance; STI-1 physically interacts with a number of proteins including HSP-1/Hsp70 and DAF-21/Hsp90, as well as proteins involved in translation and localized to the endoplasmic reticulum; a STI-1::GFP reporter is widely expressed in embryos as well as larvae and adults, with expression found in the pharynx, intestine, neurons, vulva, body wall muscles and male sensory rays; STI-1 appears to be a cytoplasmic protein. | Paper_evidence | WBPaper00033208 | ||
Curator_confirmed | WBPerson1843 | |||||
Date_last_updated | 23 Jan 2011 00:00:00 | |||||
Automated_description | Enables ATPase inhibitor activity; Hsp70 protein binding activity; and Hsp90 protein binding activity. Involved in determination of adult lifespan; reproduction; and response to heat. Located in cytoplasm. Expressed in several structures, including gonad; male-specific anatomical entity; pharyngeal muscle cell; touch receptor neurons; and vulva. Is an ortholog of human STIP1 (stress induced phosphoprotein 1). | Paper_evidence | WBPaper00065943 | |||
Curator_confirmed | WBPerson324 | |||||
WBPerson37462 | ||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
Date_last_updated | 29 Nov 2023 00:00:00 | |||||
Molecular_info | Corresponding_CDS | R09E12.3 | ||||
Corresponding_transcript | R09E12.3.1 | |||||
Other_sequence (119) | ||||||
Associated_feature | WBsf646649 | |||||
WBsf981885 | ||||||
WBsf999212 | ||||||
WBsf231366 | ||||||
Experimental_info | RNAi_result (13) | |||||
Expr_pattern (12) | ||||||
Drives_construct | WBCnstr00002530 | |||||
WBCnstr00013422 | ||||||
WBCnstr00013657 | ||||||
WBCnstr00025448 | ||||||
WBCnstr00038165 | ||||||
WBCnstr00038166 | ||||||
WBCnstr00038167 | ||||||
WBCnstr00042002 | ||||||
Construct_product | WBCnstr00013657 | |||||
WBCnstr00025448 | ||||||
Regulate_expr_cluster | WBPaper00033208:STI-1_interacting | |||||
Antibody | WBAntibody00001936 | |||||
WBAntibody00001948 | ||||||
Microarray_results (20) | ||||||
Expression_cluster (147) | ||||||
Interaction (116) | ||||||
Map_info | Map | V | Position | -19.953 | ||
Positive | Positive_clone | R09E12 | Inferred_automatically | From sequence, transcript, pseudogene data | ||
Pseudo_map_position | ||||||
Reference (18) | ||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||
[200811 gw3] Modified Map position as it was a reverse physical that could not be fixed by automated methods. (-19.9512) | ||||||
Method | Gene |