WormBase Tree Display for Gene: WBGene00021286
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| WBGene00021286 | SMap | S_parent | Sequence | Y24D9A | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | tald-1 | Person_evidence | WBPerson21677 | |||||
| WBPerson8779 | |||||||||
| Sequence_name | Y24D9A.8 | ||||||||
| Molecular_name | Y24D9A.8a | ||||||||
| Y24D9A.8a.1 | |||||||||
| CE28974 | |||||||||
| Y24D9A.8b | |||||||||
| CE30402 | |||||||||
| Y24D9A.8b.1 | |||||||||
| Other_name | CELE_Y24D9A.8 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | tald-1 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:04 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 04 Jan 2016 15:29:00 | WBPerson2970 | Name_change | CGC_name | tald-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | tald | ||||||||
| Allele (40) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (12) | |||||||||
| Contained_in_operon | CEOP4120 | ||||||||
| Ortholog (36) | |||||||||
| Paralog | WBGene00022204 | Caenorhabditis elegans | From_analysis | modENCODE_Pseudogenes | |||||
| Structured_description | Concise_description | Y24D9A.8 is orthologous to the human gene Transaldolase 1 (TALDO1), a key enzyme in the pentose phosphate pathway, which provides ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. | Paper_evidence | WBPaper00038491 | |||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson1823 | |||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 26 Jun 2012 00:00:00 | ||||||||
| Automated_description | Predicted to enable transaldolase activity. Predicted to be involved in pentose-phosphate shunt, non-oxidative branch. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in carbohydrate metabolic disorder. Is an ortholog of human TALDO1 (transaldolase 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:2978 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11559) | ||||
| Disease_relevance | The human gene Transaldolase 1 (TALDO1; orthologous to elegans Y24D9A.8), a key enzyme in the pentose phosphate pathway, provides ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis; mutations in TALDO1 are associated with Transaldolase deficiency. | Homo sapiens | Accession_evidence | OMIM | 606003 | ||||
| 602063 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 26 Jun 2012 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | Y24D9A.8a | |||||||
| Y24D9A.8b | |||||||||
| Corresponding_transcript | Y24D9A.8a.1 | ||||||||
| Y24D9A.8b.1 | |||||||||
| Other_sequence (82) | |||||||||
| Associated_feature | WBsf645921 | ||||||||
| WBsf645922 | |||||||||
| WBsf659787 | |||||||||
| WBsf228192 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00109893 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00106935 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00109926 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00109959 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00033265 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00058290 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00109986 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00055720 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00109123 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1016285 | ||||||||
| Expr1039279 | |||||||||
| Expr1159244 | |||||||||
| Expr2017294 | |||||||||
| Expr2035429 | |||||||||
| Microarray_results (37) | |||||||||
| Expression_cluster (134) | |||||||||
| Interaction (73) | |||||||||
| Map_info | Map | IV | Position | 0.196743 | |||||
| Positive | Positive_clone | Y24D9A | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00031648 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00051000 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00062388 | |||||||||
| WBPaper00062747 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
