WormBase Tree Display for Interaction: WBInteraction000504096
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| WBInteraction000504096 | Interaction_type | Regulatory | Change_of_localization | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00003239 | Interactor_type | Trans_regulated | |
| Expr_pattern | Expr8941 | ||||
| Transgene | WBTransgene00001040 | ||||
| Construct | WBCnstr00001031 | ||||
| WBGene00003657 | Interactor_type | Trans_regulator | |||
| Interaction_summary | In the LCs of L3 stage wild-type males, MIG-2::GFP was evenly distributed throughout the membrane, but during the L4 stage MIG-2 became polarized to the adherent, ventral side. In L4 stage nhr-67(RNAi) males, however, only five of 26 LCs showed MIG-2::GFP membrane polarization to the adherent side. It might be that MIG-2 does not localize properly in nhr-67(RNAi) males because the LC is not positioned in L4 to access spatially restricted ECM components. | ||||
| Detection_method | Construct | ||||
| Reporter_gene | [mig-2::gfp] | ||||
| Transgene | |||||
| Regulation_result | Positive_regulate | Life_stage | WBls:0000038 | ||
| Anatomy_term | WBbt:0005062 | ||||
| Subcellular_localization | adherent, ventral side of LC | ||||
| Paper | WBPaper00035457 |
