WormBase Tree Display for Interaction: WBInteraction000532969
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| WBInteraction000532969 | Interaction_type | Genetic | Partial_suppression | ||
|---|---|---|---|---|---|
| GI_module_two | Sub_suppressing | ||||
| Interactor | Interactor_overlapping_gene | WBGene00016946 | Interactor_type | Effector | |
| Other_interactor | human TDP-43(M337V) | Interactor_type | Affected | ||
| Variation_interactor | WBVar00252707 | Interactor_type | Effector | ||
| Interaction_summary | Mutants partially restored motor function as indicated by more coordinated, natural, and rapid movement than the parental TDP-43 transgenic strain. To quantify these observations, we measured the number of spontaneous head movements and the number of body movements of individual animals. Mutants had visible decreases in TDP-43 phosphorylation. | ||||
| Throughput | Low_throughput | ||||
| Interaction_phenotype | WBPhenotype:0000643 | ||||
| WBPhenotype:0001351 | |||||
| Unaffiliated_transgene | WBTransgene00019820 | ||||
| Paper | WBPaper00042050 |
