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| WBPicture0000012738 | Description | Figure 5. TBC-8 localizes to the Golgi-endosomal interface. (A) The subcellular localization of fluorescently-labeled TBC-8 expressed in motoneurons was analyzed by confocal microscopy. Fluorescently-labeled-TBC-8 localized partially with medial and trans-Golgi markers and showed full co-localization with the early endosomal marker mCherry-RAB-5. No co-localization to RAB-7-positive late endosomes was observed. (B) In motoneurons, mCherry-RAB-2 localizes to the Golgi (left cell body; cell boundary is highlighted by a dashed line). However, when YFP-TBC-8 is overexpressed, mCherry-RAB-2 is redistributed to the cytosol (right cell body). Manns: mannosidase II, TGN: trans-Golgi network. Scale bars represent 3 mm | |||
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| Name | FigN.jpg | ||||
| Depict | Expr_pattern | Expr10033 | |||
| Cellular_component | GO:0005769 | ||||
| GO:0005794 | |||||
| Acknowledgment | Template | Reprinted from <Journal_URL>, <Article_URL>. <Publisher_URL> <Publication_year>. | |||
| Publication_year | 2012 | ||||
| Article_URL | DOI | id | 10.1371/journal.pgen.1002722 | ||
| Journal_URL | PLoSGenetics | ||||
| Publisher_URL | PLoS | ||||
| Reference | WBPaper00041154 |
