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| WBPicture0000014448 | Description | Figure 3. SCAV-3 is widely distributed and localizes to lysosomes. (A-F') Differential interference contrast (DIC) and confocal fluorescent images of wildtype expressing SCAV-3::GFP driven by the scav-3 promoter. (G-H'') Confocal fluorescent images of the hypodermis in wild type expressing SCAV-3::GFPand LAAT-1::mCherry (G-G'') or SCAV-3::GFP and NUC-1::mCherry (H-H'''). SCAV-3 colocalizes with LAAT-1 and NUC-1 to both vesicular (arrowheads)and tubular (arrows) lysosomes. (I and J) Fluorescent images of wild-type animals expressing SCAV-3::sfGFP (I) or SCAV-3(AAA)::sfGFP (J) in the pharynx. SCAV-3(AAA)::sfGFP localizes to plasma membranes (arrows). (K-S) Confocal fluorescent images of wild type expressing LMP-1::sfGFP (K-R) orLMP-2::sfGFP (S). (T) The mean total fluorescence intensity of LMP-1::sfGFP in different cell types was measured, and the normalized florescence intensityis shown. At least 15 animals were scored in each cell type. Data are shown as mean +- SD. One-way ANOVA with Tukey's posttest was performed tocompare all the other datasets with hypodermis. *, P < 0.05; **, P < 0.0001. Bars, 10 um. | |||
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| Name | FigC.jpg | ||||
| Crop | Crop_picture | WBPicture0000014449 | |||
| Depict | Expr_pattern | Expr13186 | |||
| Anatomy | WBbt:0003681 | ||||
| WBbt:0005733 | |||||
| WBbt:0005741 | |||||
| WBbt:0005828 | |||||
| WBbt:0006748 | |||||
| Cellular_component | GO:0005764 | ||||
| Acknowledgment | Template | WormBase thanks <Journal_URL> for permission to reproduce figures from this article. Reprinted from <Article_URL>. Copyright (<Publication_year>) with permission from <Publisher_URL>. The user must not use the Work for commercial purposes. If the user shares, alters, transforms, or builds upon the Work, the user may distribute the resulting work only under the same license the user received from <Publisher_URL>. | |||
| Publication_year | 2016 | ||||
| Article_URL | DOI | id | 10.1083/jcb.201602090 | ||
| Journal_URL | TheJournalofCellBiology | ||||
| Publisher_URL | TheRockefellerUniversityPress | ||||
| Reference | WBPaper00050406 |
