WormBase Tree Display for RNAi: WBRNAi00110049

WBRNAi00110049 Homol: Homol_homol: Y47G6A:RNAi
  Sequence_info: PCR_product: sjj_Y47G6A_247.i
  Experiment: Genotype: jIs01 [rol-6(su1006); myo-3::gfp]
    Delivered_by: Bacterial_feeding
  Inhibits: Predicted_gene: Y47G6A.8 Inferred_automatically: RNAi_primary
    Gene: WBGene00000794 Inferred_automatically: RNAi_primary
    Transcript: Y47G6A.8.1 Inferred_automatically: RNAi_primary
  Species: Caenorhabditis elegans
  Reference: WBPaper00046120
  Phenotype_not_observed: WBPhenotype:0001889 Remark: "Next, we performed RNAi against a set of 10 knockdowns previously shown to produce embryonic lethality [icd-1 (inhibitor of celldeath), snr-6 (small nuclear ribonucleoprotein), npp-20 (nuclear pore complex protein), vha-9 (vaculolar ATPase), nap-1 (nucleosome assembly protein), ufd-1 (ubiquitin fusion degradation), fnta-1 (farnesyltransferase), pbs-2 (proteasome b-subunit), cyb-2.1 (cyclin B), and crn-1 (cell death related nuclease)]. In each case, we found embryonic lethality as expected. When these genes were knocked down in fully developed adults, we further found both increased protein degradation and loss of mitochondrial reticular structure but no defects in the sarcomere structure."
      EQ_annotations: GO_term: GO:0030017 PATO:0000460
  Remark: crn-1 RNAi. Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation.
  Method: RNAi