WormBase Tree Display for Variation: WBVar00000113
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| WBVar00000113 | Evidence | Paper_evidence | WBPaper00026850 | |||||
|---|---|---|---|---|---|---|---|---|
| Name | Public_name | ak41 | ||||||
| Sequence_details | Mapping_target | C35B8 | ||||||
| Type_of_mutation | Insertion | |||||||
| SeqStatus | Pending_curation | |||||||
| Variation_type | Allele | |||||||
| Transposon_insertion | Tc1 | |||||||
| Origin | Species | Caenorhabditis elegans | ||||||
| Laboratory | VM | |||||||
| Status | Live | |||||||
| Affects | Gene | WBGene00006887 | ||||||
| Description | Phenotype (14) | |||||||
| Phenotype_not_observed | WBPhenotype:0000625 | Paper_evidence | WBPaper00046036 | |||||
| Curator_confirmed | WBPerson557 | |||||||
| Remark | Normal synapse formation observed in vav-1(ak41) mutant worms. | Paper_evidence | WBPaper00046036 | |||||
| Curator_confirmed | WBPerson557 | |||||||
| WBPhenotype:0000707 | Paper_evidence | WBPaper00026850 | ||||||
| Curator_confirmed | WBPerson48 | |||||||
| Phenotype_assay | Genotype | vav-1(ak41) | Paper_evidence | WBPaper00026850 | ||||
| Curator_confirmed | WBPerson48 | |||||||
| WBPhenotype:0000709 | Paper_evidence | WBPaper00026850 | ||||||
| Curator_confirmed | WBPerson48 | |||||||
| Phenotype_assay | Genotype | vav-1(ak41) | Paper_evidence | WBPaper00026850 | ||||
| Curator_confirmed | WBPerson48 | |||||||
| WBPhenotype:0000816 | Paper_evidence | WBPaper00046036 | ||||||
| Curator_confirmed | WBPerson557 | |||||||
| Remark | Normal neuronal development observed in vav-1(ak41) mutant worms. | Paper_evidence | WBPaper00046036 | |||||
| Curator_confirmed | WBPerson557 | |||||||
| WBPhenotype:0000845 | Paper_evidence | WBPaper00046036 | ||||||
| Curator_confirmed | WBPerson557 | |||||||
| Remark | Analysis of levamisole-treated animals revealed that vav-1(ak41) mutants responded like WT animals. | Paper_evidence | WBPaper00046036 | |||||
| Curator_confirmed | WBPerson557 | |||||||
| Phenotype_assay | Treatment | Animals were paralyzed with 100 mM levamisole. | Paper_evidence | WBPaper00046036 | ||||
| Curator_confirmed | WBPerson557 | |||||||
| WBPhenotype:0001188 | Paper_evidence | WBPaper00026850 | ||||||
| Curator_confirmed | WBPerson48 | |||||||
| Phenotype_assay | Genotype | vav-1(ak41) | Paper_evidence | WBPaper00026850 | ||||
| Curator_confirmed | WBPerson48 | |||||||
| WBPhenotype:0001189 | Paper_evidence | WBPaper00026850 | ||||||
| Curator_confirmed | WBPerson48 | |||||||
| Phenotype_assay | Treatment | light microscope | Paper_evidence | WBPaper00026850 | ||||
| Curator_confirmed | WBPerson48 | |||||||
| Genotype | vav-1(ak41) | Paper_evidence | WBPaper00026850 | |||||
| Curator_confirmed | WBPerson48 | |||||||
| Reference | WBPaper00026850 | |||||||
| WBPaper00065282 | ||||||||
| WBPaper00046036 | ||||||||
| Remark | Tc1 insertion in 5th exon removes 2kb of genomic sequence and introduces premature stop. | Paper_evidence | WBPaper00026850 | |||||
| Method | Transposon_insertion |
