WormBase Tree Display for Variation: WBVar00000465

WBVar00000465 Evidence: Paper_evidence: WBPaper00028483
  Name: Public_name: bn23
    Other_name: Y2H9A.1.1:c.2173-1G>A
    HGVSg: CHROMOSOME_V:g.13434384C>T
  Sequence_details: SMap: S_parent: Sequence: Y2H9A
    Flanking_sequences: tcaacattttgattttatttcttattttca gccggaaagaacggaaccgcatctaagaaa
    Mapping_target: Y2H9A
    Type_of_mutation: Substitution: g a Paper_evidence: WBPaper00028483
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00034440
    Laboratory: SS
    Status: Live
  Affects: Gene: WBGene00003222
    Transcript: Y2H9A.1.1 VEP_consequence: splice_acceptor_variant
        VEP_impact: HIGH
        HGVSc: Y2H9A.1.1:c.2173-1G>A
        Intron_number: 8/11
    Interactor: WBInteraction000050871
      WBInteraction000050877
      WBInteraction000050883
      WBInteraction000050886
      WBInteraction000050890
      WBInteraction000502764
      WBInteraction000541585
  Genetics: Interpolated_map_position: V 5.33953
    Mapping_data: In_2_point: 6090
        6092
        6093
        6094
        6095
        6096
        6097
        6098
      In_multi_point: 2157
        2161
        2162
        2163
        2164
        2165
        2166
      In_pos_neg_data: 6685
        6686
  Description: Phenotype: WBPhenotype:0000154 Paper_evidence: WBPaper00001477
        Curator_confirmed: WBPerson2021
        Remark: bn23 homozygous mothers have a reduced average brood size compared to wild-type controls Paper_evidence: WBPaper00001477
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00001477
          Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000057 PATO:0000460 Paper_evidence: WBPaper00001477
                Curator_confirmed: WBPerson2021
        Phenotype_assay: Temperature: 16 C , 25 C Paper_evidence: WBPaper00001477
              Curator_confirmed: WBPerson2021
      WBPhenotype:0000684 Paper_evidence: WBPaper00001477
        Curator_confirmed: WBPerson2021
        Remark: Mutant progeny exhibit abnormal germline proliferation during development and fail to form mature gametes Paper_evidence: WBPaper00001477
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00001477
          Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000057 PATO:0000460 Paper_evidence: WBPaper00001477
                Curator_confirmed: WBPerson2021
        Maternal: Strictly_maternal: Paper_evidence: WBPaper00001477
            Curator_confirmed: WBPerson2021
      WBPhenotype:0001504 Paper_evidence: WBPaper00001477
        Curator_confirmed: WBPerson2021
        Remark: Mes phenotype is not due to abnormalities in P granule staining Paper_evidence: WBPaper00001477
            Curator_confirmed: WBPerson2021
        Penetrance: Complete: Paper_evidence: WBPaper00001477
              Curator_confirmed: WBPerson2021
          Range: 100 100 Paper_evidence: WBPaper00001477
                Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00001477
          Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000057 PATO:0000460 Paper_evidence: WBPaper00001477
                Curator_confirmed: WBPerson2021
        Maternal: Strictly_maternal: Paper_evidence: WBPaper00001477
            Curator_confirmed: WBPerson2021
        Phenotype_assay: Temperature: 16 C , 25 C Paper_evidence: WBPaper00001477
              Curator_confirmed: WBPerson2021
    Phenotype_not_observed: WBPhenotype:0000052 Paper_evidence: WBPaper00001477
        Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00001477
          Curator_confirmed: WBPerson2021
  Reference: WBPaper00001477
    WBPaper00014214
  Method: Substitution_allele