WormBase Tree Display for Variation: WBVar00000539

WBVar00000539 Evidence: Paper_evidence: WBPaper00029153
      WBPaper00028877
  Name: Public_name: br2
    HGVSg: CHROMOSOME_X:g.15757792_15758102del
  Sequence_details: SMap: S_parent: Sequence: ZK678
    Flanking_sequences: gaaggattcgacaagcactcatttgacgac ttaattttgttcttctataacgagtgtgtg
    Mapping_target: ZK678
    Type_of_mutation: Deletion
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00004761
    Laboratory: DC
    Status: Live
  Affects: Gene: WBGene00044630
    Transcript: ZK678.8.1 VEP_consequence: coding_sequence_variant,3_prime_UTR_variant
        VEP_impact: MODIFIER
        cDNA_position: 971-?
        CDS_position: 940-?
        Protein_position: 314-?
        Exon_number: 9-10/10
  Genetics: Interpolated_map_position: X 22.9587
  Description: Phenotype: WBPhenotype:0001209 Paper_evidence: WBPaper00029153
        Curator_confirmed: WBPerson712
        Remark: Animals are Skd on both E.coli (OP50) as well as Yersinia lawns. Paper_evidence: WBPaper00029153
            Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00029153
          Curator_confirmed: WBPerson712
      WBPhenotype:0001212 Paper_evidence: WBPaper00029153
        Curator_confirmed: WBPerson712
        Remark: Animals are hypersensitive to alkaline hypochlorite treatment, based on the time it took for the last animal to stop thrashing when immersed in alkaline hypochlorite and the time the first animal suffered a visible breach in its cuticle. Paper_evidence: WBPaper00029153
            Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00029153
          Curator_confirmed: WBPerson712
      WBPhenotype:0001411 Paper_evidence: WBPaper00029153
        Curator_confirmed: WBPerson712
        Remark: As assayed by staining with wheat germ agglutinin (WGA). Wild type worms exhibit no staining except at the vulva. Paper_evidence: WBPaper00029153
            Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00029153
          Curator_confirmed: WBPerson712
      WBPhenotype:0001413 Paper_evidence: WBPaper00029153
        Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00029153
          Curator_confirmed: WBPerson712
      WBPhenotype:0001420 Paper_evidence: WBPaper00029153
        Curator_confirmed: WBPerson712
        Penetrance: Complete: Paper_evidence: WBPaper00029153
              Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00029153
          Curator_confirmed: WBPerson712
        Paternal: Paper_evidence: WBPaper00029153
          Curator_confirmed: WBPerson712
        Phenotype_assay: Genotype: + or him-5 Paper_evidence: WBPaper00029153
              Curator_confirmed: WBPerson712
      WBPhenotype:0001689 Paper_evidence: WBPaper00029153
        Curator_confirmed: WBPerson712
        Remark: Animals do not bind L1 specific mAb M37 Paper_evidence: WBPaper00029153
            Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00029153
          Curator_confirmed: WBPerson712
      WBPhenotype:0001918 Paper_evidence: WBPaper00052991
        Curator_confirmed: WBPerson38714
    Phenotype_not_observed: WBPhenotype:0000676 Paper_evidence: WBPaper00029153
        Curator_confirmed: WBPerson712
        Remark: No growth defects were observed on standard E.coli OP50. In addition animals grew at the same rate on Yersinia pestis and Y. pseudotuburculosis as they did when fed E.coli. Paper_evidence: WBPaper00029153
            Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00029153
          Curator_confirmed: WBPerson712
  Reference: WBPaper00029153
    WBPaper00052991
  Method: Deletion_allele