WormBase Tree Display for Variation: WBVar00000544

WBVar00000544 Evidence: Paper_evidence: WBPaper00029153
  Name: Public_name: br7
  Sequence_details: SeqStatus: Pending_curation
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00005602
    Laboratory: DC
    Status: Live
  Affects: Gene: WBGene00050876
  Description: Phenotype: WBPhenotype:0001212 Paper_evidence: WBPaper00029153
        Curator_confirmed: WBPerson712
        Remark: Animals exhibit slightly fragile cuticles, based on the time it took for the last animal to stop thrashing when immersed in alkaline hypochlorite and the time the first animal suffered a visible breach in its cuticle. Paper_evidence: WBPaper00029153
            Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00029153
          Curator_confirmed: WBPerson712
      WBPhenotype:0001420 Paper_evidence: WBPaper00029153
          WBPaper00031925
        Curator_confirmed: WBPerson712
        Remark: Animals are completely resistant to attachment of biofilm produced by Xenorhabdus nematophila. Paper_evidence: WBPaper00031925
            Curator_confirmed: WBPerson712
        Penetrance: Complete: Paper_evidence: WBPaper00029153
                WBPaper00031925
              Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00029153
          Curator_confirmed: WBPerson712
        Phenotype_assay: Treatment: Biofilm formation on adult worms was assessed for worms incubated 24-48 hours on the bacterial lawn. Alternatively, gravid adults were allowed to lay eggs on bacterial lawns for several hours, then removed and larvae were assessed for biofilm attachment the next day. Paper_evidence: WBPaper00031925
              Curator_confirmed: WBPerson712
    Phenotype_not_observed: WBPhenotype:0000676 Paper_evidence: WBPaper00029153
        Curator_confirmed: WBPerson712
        Remark: No growth defects were observed on standard E.coli OP50. In addition animals grew at the same rate on Yersinia pestis and Y. pseudotuburculosis as they did when fed E.coli. Paper_evidence: WBPaper00029153
            Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00029153
          Curator_confirmed: WBPerson712
      WBPhenotype:0001209 Paper_evidence: WBPaper00029153
        Curator_confirmed: WBPerson712
        Remark: Motion was assayed on E.coli lawns. Paper_evidence: WBPaper00029153
            Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00029153
          Curator_confirmed: WBPerson712
      WBPhenotype:0001411 Paper_evidence: WBPaper00029153
        Curator_confirmed: WBPerson712
        Remark: As assayed by staining with wheat germ agglutinin (WGA). Wild type worms exhibit no staining except at the vulva. Paper_evidence: WBPaper00029153
            Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00029153
          Curator_confirmed: WBPerson712
      WBPhenotype:0001413 Paper_evidence: WBPaper00029153
        Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00029153
          Curator_confirmed: WBPerson712
      WBPhenotype:0001687 Paper_evidence: WBPaper00029153
        Curator_confirmed: WBPerson712
        Remark: Binding of L1 specific mAb M37 is similar to wild type. Paper_evidence: WBPaper00029153
            Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00029153
          Curator_confirmed: WBPerson712
  Reference: WBPaper00031925
    WBPaper00029153
  Method: Allele