WormBase Tree Display for Variation: WBVar00054157

WBVar00054157 Evidence: Paper_evidence: WBPaper00027321
  Name: Public_name: cg121
    Other_name: T21B6.1.2:c.220-162_*502del
      T21B6.1.1:c.220-162_*502del
    HGVSg: CHROMOSOME_X:g.10920730_10923124del
  Sequence_details: SMap: S_parent: Sequence: T21B6
    Flanking_sequences: agagagcatacaagaaataagaaaatcacc gtttcagaaatttctttgatgactcacgtg
    Mapping_target: T21B6
    Type_of_mutation: Deletion
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00005032
      WBStrain00005038
      WBStrain00005039
    Laboratory: CH
    Status: Live
  Affects: Gene: WBGene00000961
    Transcript: T21B6.1.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,3_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: T21B6.1.1:c.220-162_*502del
        cDNA_position: ?-2370
        Intron_number: 3-6/7
        Exon_number: 4-8/8
      T21B6.1.2 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,3_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: T21B6.1.2:c.220-162_*502del
        cDNA_position: ?-2267
        Intron_number: 2-5/6
        Exon_number: 3-7/7
  Genetics: Interpolated_map_position: X 2.70094
  Description: Phenotype: WBPhenotype:0000688 Paper_evidence: WBPaper00032026
        Curator_confirmed: WBPerson2021
        Remark: Mutation of the dgn-1 gene leads to sterility Paper_evidence: WBPaper00032026
            Curator_confirmed: WBPerson2021
        Variation_effect: Null: Paper_evidence: WBPaper00032026
            Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000041 PATO:0000460 Paper_evidence: WBPaper00032026
                Curator_confirmed: WBPerson2021
      WBPhenotype:0000977 Paper_evidence: WBPaper00032026
        Curator_confirmed: WBPerson2021
        Remark: Gonads of dgn-1 mutant worms were variably misshapen and burst during development. dgn-1(cg121) hermaphrodite gonads did not have any localized breaks as did the ten-1(ok641) gonads. Paper_evidence: WBPaper00032026
            Curator_confirmed: WBPerson2021
        Variation_effect: Null: Paper_evidence: WBPaper00032026
            Curator_confirmed: WBPerson2021
        EQ_annotations: Anatomy_term: WBbt:0005785 PATO:0000460 Paper_evidence: WBPaper00032026
                Curator_confirmed: WBPerson2021
    Phenotype_not_observed: WBPhenotype:0000709 Paper_evidence: WBPaper00032026
        Curator_confirmed: WBPerson2021
        Remark: The pharynx of the dgn-1 mutant worms shows no obvious defects Paper_evidence: WBPaper00032026
            Curator_confirmed: WBPerson2021
        Variation_effect: Null: Paper_evidence: WBPaper00032026
            Curator_confirmed: WBPerson2021
        EQ_annotations: Anatomy_term: WBbt:0003681 PATO:0000460 Paper_evidence: WBPaper00032026
                Curator_confirmed: WBPerson2021
          Life_stage: WBls:0000023 PATO:0000460 Paper_evidence: WBPaper00032026
                Curator_confirmed: WBPerson2021
        Phenotype_assay: Genotype: urEx131[LAM-1::GFP] Paper_evidence: WBPaper00032026
              Curator_confirmed: WBPerson2021
  Reference: WBPaper00032026
  Method: Deletion_allele