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WormBase Tree Display for Variation: WBVar00087753

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Name Class

WBVar00087753NamePublic_namehc34
Sequence_detailsSeqStatusPending_curation
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
StrainWBStrain00000367
LaboratoryBA
StatusLive
AffectsGeneWBGene00001419
GeneticsMapping_dataIn_2_point206
In_multi_point201
DescriptionPhenotypeWBPhenotype:0000357Paper_evidenceWBPaper00001075
WBPaper00000495
Curator_confirmedWBPerson2021
WBPerson712
RemarkAt the permissive temperature, ts mutants produced 100 to 300 progeny and less than 65 unfertilized eggs, which were laid late in the life cycle, like those of wild-type hermaphrodites. At the restrictive temperature of 25 deg C, animals produced only a few progeny and laid 72 to 282 unfertilized eggs. Mutants produce fewer eggs than wild type at both temperatures.Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
PenetranceIncompletePaper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
RecessivePaper_evidenceWBPaper00001075
Curator_confirmedWBPerson2021
EQ_annotationsLife_stageWBls:0000057PATO:0000460Paper_evidenceWBPaper00001075
Curator_confirmedWBPerson2021
Temperature_sensitiveHeat_sensitivePaper_evidenceWBPaper00001075
Curator_confirmedWBPerson2021
25Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
WBPhenotype:0000387Person_evidenceWBPerson261
Curator_confirmedWBPerson712
RemarkHermaphrodites and males grown at 25C produce nonfunctional nonmotile sperm. Self-fertility 6% (25C) 40% (16C). TSP L4. ES2 (adult)Person_evidenceWBPerson261
Curator_confirmedWBPerson712
EQ_annotationsLife_stageWBls:0000057PATO:0000460Person_evidenceWBPerson261
Curator_confirmedWBPerson712
WBls:0000056PATO:0000460Person_evidenceWBPerson261
Curator_confirmedWBPerson712
Temperature_sensitiveHeat_sensitive25Person_evidenceWBPerson261
Curator_confirmedWBPerson712
Ease_of_scoringES2_Difficult_to_scorePerson_evidenceWBPerson261
Curator_confirmedWBPerson712
WBPhenotype:0000688Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
RemarkThis allele is very leaky. At the permissive temperature, ts mutants produced 100 to 300 progeny and less than 65 unfertilized eggs, which were laid late in the life cycle, like those of wild-type hermaphrodites. At the restrictive temperature of 25 deg C, animals produced only a few progeny and laid 72 to 282 unfertilized eggs.Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
PenetranceIncompletePaper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
Temperature_sensitiveHeat_sensitive25Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
WBPhenotype:0000694Person_evidenceWBPerson261
Curator_confirmedWBPerson712
RemarkSelf-fertility 6% (25C) 40% (16C). TSP L4.Person_evidenceWBPerson261
Curator_confirmedWBPerson712
EQ_annotationsLife_stageWBls:0000057PATO:0000460Person_evidenceWBPerson261
Curator_confirmedWBPerson712
Temperature_sensitiveHeat_sensitive25Person_evidenceWBPerson261
Curator_confirmedWBPerson712
WBPhenotype:0000806Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
RemarkAnimals are fertilization defective. Animals have a short (5-10 hrs) temperature sensitive period (TSP) late in their development.Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
PenetranceIncompletePaper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
Temperature_sensitiveHeat_sensitive25Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
WBPhenotype:0001360Paper_evidenceWBPaper00001075
Curator_confirmedWBPerson2021
RecessivePaper_evidenceWBPaper00001075
Curator_confirmedWBPerson2021
EQ_annotationsLife_stageWBls:0000057PATO:0000460Paper_evidenceWBPaper00001075
Curator_confirmedWBPerson2021
Temperature_sensitiveHeat_sensitivePaper_evidenceWBPaper00001075
Curator_confirmedWBPerson2021
WBPhenotype:0001720Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
RemarkNonfunctional sperm of fer hermaphrodites are progressively lost fro the spermathecae of mutant hermaphrodites. by the time 40-70 oocytes have passed through the spermathecae of sterile hermaphrodites, most of the sperm have been swept out rather than migrating back through the spermathecal valve.Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
Temperature_sensitiveHeat_sensitive25Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
Phenotype_not_observedWBPhenotype:0000033Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
RemarkAnimals grow and develop at the same rate as wild type, initiating egg laying at 45 hr post-hatching, as do N2 hermaphrodites.Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
WBPhenotype:0000186Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
RemarkOocytes are produced and are capable of being fertilized.Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
WBPhenotype:0000670Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
RemarkAt the start of their egg-laying period, 45 hr post-hatching at 25 deg C, the spermathecae of these hermaphrodites contain over 170 sperm.Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
WBPhenotype:0000676Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
RemarkAnimals grow and develop at the same rate as wild type, initiating egg laying at 45 hr post-hatching, as do N2 hermaphrodites.Paper_evidenceWBPaper00000495
Curator_confirmedWBPerson712
ReferenceWBPaper00001075
WBPaper00000495
WBPaper00015949
MethodAllele