WormBase Tree Display for Variation: WBVar00088021

WBVar00088021 Evidence: Paper_evidence: WBPaper00003779
  Name: Public_name: it44
    Other_name: ZK1127.11.1:c.1216G>T
      CE24714:p.His406Tyr
    HGVSg: CHROMOSOME_II:g.7068199C>A
  Sequence_details: SMap: S_parent: Sequence: ZK1127
    Flanking_sequences: gctatccggcactttgtagctgttcagttg atttggcaagacagacttatgaagaaataa
    Mapping_target: ZK1127
    Type_of_mutation: Substitution: c t Paper_evidence: WBPaper00003779
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00023558
    Laboratory: KK
    Status: Live
  Affects: Gene: WBGene00001872
    Transcript: ZK1127.11.1 (12)
    Interactor: WBInteraction000576752
  Genetics: Interpolated_map_position: II 0.477081
    Mapping_data: In_pos_neg_data: 4475
  Description: Phenotype: WBPhenotype:0000274 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: 95% dead eggs Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Temperature_sensitive: Heat_sensitive: Person_evidence: WBPerson261
              Curator_confirmed: WBPerson712
      WBPhenotype:0001174 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: probable generalized nondisjunction, meiotic defect Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Temperature_sensitive: Heat_sensitive: Person_evidence: WBPerson261
              Curator_confirmed: WBPerson712
      WBPhenotype:0001175 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: viable self-progeny 2-40% male Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Temperature_sensitive: Heat_sensitive: Person_evidence: WBPerson261
              Curator_confirmed: WBPerson712
      WBPhenotype:0001814 Paper_evidence: WBPaper00061682
        Curator_confirmed: WBPerson712
        Remark: high frequency of univalents observed in him-14(it44ts) mutant oocytes at the semi-permissive temperature of 20C Paper_evidence: WBPaper00061682
            Curator_confirmed: WBPerson712
        Temperature_sensitive: Heat_sensitive: Paper_evidence: WBPaper00061682
              Curator_confirmed: WBPerson712
        Phenotype_assay: Temperature: 20 Deg C Paper_evidence: WBPaper00061682
              Curator_confirmed: WBPerson712
  Reference: WBPaper00017195
    WBPaper00022704
    WBPaper00002848
    WBPaper00061682
  Method: Substitution_allele