WormBase Tree Display for Variation: WBVar00088100

WBVar00088100 Evidence: Paper_evidence: WBPaper00024456
  Name: Public_name: jh131
  Sequence_details: Mapping_target: ZK455
    Type_of_mutation: Deletion
    SeqStatus: Pending_curation
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00023533
    Laboratory: KJ
    Status: Live
  Affects: Gene: WBGene00000040
  Description: Phenotype: WBPhenotype:0000039 Paper_evidence: WBPaper00024456
        Curator_confirmed: WBPerson557
        Remark: aco-1(jh131) mutant animals lacking ACO-1 show significantly reduced life-span upon iron stress. Paper_evidence: WBPaper00024456
            Curator_confirmed: WBPerson557
        Phenotype_assay: Treatment: For life-span analysis, worms were grown on either NGM plates or NGM plates supplemented with ferric ammonium citrate at 6.6 mg/ml (FAC iron stress plate) at 20 C. Paper_evidence: WBPaper00024456
              Curator_confirmed: WBPerson557
          Temperature: 20 Paper_evidence: WBPaper00024456
              Curator_confirmed: WBPerson557
      WBPhenotype:0000154 Paper_evidence: WBPaper00024456
        Curator_confirmed: WBPerson557
        Remark: Slightly smaller brood size than wild-type (data not shown). Paper_evidence: WBPaper00024456
            Curator_confirmed: WBPerson557
      WBPhenotype:0002046 Paper_evidence: WBPaper00024456
        Curator_confirmed: WBPerson557
        Remark: aco-1(jh131) mutant animals lacking ACO-1 show significantly reduced life-span upon iron stress. Paper_evidence: WBPaper00024456
            Curator_confirmed: WBPerson557
        Phenotype_assay: Treatment: For life-span analysis, worms were grown on either NGM plates or NGM plates supplemented with ferric ammonium citrate at 6.6 mg/ml (FAC iron stress plate) at 20 C. Paper_evidence: WBPaper00024456
              Curator_confirmed: WBPerson557
          Temperature: 20 Paper_evidence: WBPaper00024456
              Curator_confirmed: WBPerson557
    Phenotype_not_observed: WBPhenotype:0000520 Paper_evidence: WBPaper00024456
        Curator_confirmed: WBPerson557
        Remark: Authors state this mutant has normal morphology. Paper_evidence: WBPaper00024456
            Curator_confirmed: WBPerson557
      WBPhenotype:0000676 Paper_evidence: WBPaper00024456
        Curator_confirmed: WBPerson557
        Remark: Authors state this mutant has a normal growth rate. Paper_evidence: WBPaper00024456
            Curator_confirmed: WBPerson557
  Reference: WBPaper00024456
  Remark: Allele is a 1567bp deletion removing first three exons Paper_evidence: WBPaper00024456
  Method: Deletion_allele