WormBase Tree Display for Variation: WBVar00088273
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WBVar00088273 | Evidence | Paper_evidence | WBPaper00031930 | ||||||
---|---|---|---|---|---|---|---|---|---|
Name | Public_name | kr105 | |||||||
Sequence_details | Mapping_target | F09E8 | |||||||
Type_of_mutation | Insertion | ||||||||
SeqStatus | Pending_curation | ||||||||
Variation_type | Allele | ||||||||
Transposon_insertion | Mos1 | ||||||||
Origin | Species | Caenorhabditis elegans | |||||||
Laboratory | EN | ||||||||
Status | Live | ||||||||
Affects | Gene | WBGene00002974 | |||||||
Description | Phenotype | WBPhenotype:0000421 | Paper_evidence | WBPaper00031930 | |||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | Animals were less sensitive to levamisole; EC50 = 223. | Paper_evidence | WBPaper00031930 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Affected_by | Molecule | WBMol:00004019 | Paper_evidence | WBPaper00031930 | |||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0001783 | Paper_evidence | WBPaper00031930 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | The single-channel conductance of the lev-1;lev-10 mutant was 26.9 0.7 pS (n=3), which was less than the mean 30.3 0.4 pS of the lev-10 control animals (P=0.019, df=34). At 10 M levamisole, the mean closed times of receptors lacking LEV-1 subunits were not significantly different from control animals. | Paper_evidence | WBPaper00031930 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
EQ_annotations | GO_term | GO:0022834 | PATO:0000460 | Paper_evidence | WBPaper00031930 | ||||
Curator_confirmed | WBPerson712 | ||||||||
Phenotype_assay | Genotype | lev-10 | Paper_evidence | WBPaper00031930 | |||||
Curator_confirmed | WBPerson712 | ||||||||
Reference | WBPaper00031930 | ||||||||
Method | Mos_insertion |