WormBase Tree Display for Variation: WBVar00088447
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| WBVar00088447 | Evidence | Paper_evidence | WBPaper00006275 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Name | Public_name | ky399 | |||||||
| Other_name (27) | |||||||||
| HGVSg | CHROMOSOME_V:g.18497266G>A | ||||||||
| Sequence_details | SMap | S_parent | Sequence | Y51A2D | |||||
| Flanking_sequences | tttcaggccatgtttgcaagttacgtacca | aaattgccgatttgattggaaaccggcaaa | |||||||
| Mapping_target | Y51A2D | ||||||||
| Type_of_mutation | Substitution | g | a | Paper_evidence | WBPaper00006275 | ||||
| SeqStatus | Sequenced | ||||||||
| Variation_type | Allele | ||||||||
| Origin | Species | Caenorhabditis elegans | |||||||
| Strain | WBStrain00005259 | ||||||||
| Laboratory | CX | ||||||||
| Status | Live | ||||||||
| Affects | Gene | WBGene00004830 | |||||||
| Transcript (13) | |||||||||
| Genetics | Interpolated_map_position | V | 16.7476 | ||||||
| Description | Phenotype | WBPhenotype:0000010 | Paper_evidence | WBPaper00036766 | |||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | The slo-1 BK potassium channel gain-of-function allele ky399, which reduced ACh release, was hypersensitive to fluoxetine in the paralysis assay. | Paper_evidence | WBPaper00036766 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Variation_effect | Hypermorph_gain_of_function | Paper_evidence | WBPaper00036766 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Affected_by | Molecule | WBMol:00005058 | Paper_evidence | WBPaper00036766 | |||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0000017 | Paper_evidence | WBPaper00053000 | |||||||
| Curator_confirmed | WBPerson2876 | ||||||||
| Remark | Figure 2 | Paper_evidence | WBPaper00053000 | ||||||
| Curator_confirmed | WBPerson2876 | ||||||||
| WBPhenotype:0001612 | Paper_evidence | WBPaper00006275 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0001661 | Paper_evidence | WBPaper00003760 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | 2 AWC on | Paper_evidence | WBPaper00003760 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Semi_dominant | Paper_evidence | WBPaper00003760 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Anatomy_term | WBbt:0005672 | PATO:0000460 | Paper_evidence | WBPaper00003760 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Phenotype_not_observed | WBPhenotype:0000006 | Paper_evidence | WBPaper00003760 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | superficially normal egg laying | Paper_evidence | WBPaper00003760 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Semi_dominant | Paper_evidence | WBPaper00003760 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0000643 | Paper_evidence | WBPaper00003760 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | superficially normal movement | Paper_evidence | WBPaper00003760 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Semi_dominant | Paper_evidence | WBPaper00003760 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Reference | WBPaper00036766 | ||||||||
| WBPaper00006275 | |||||||||
| WBPaper00003760 | |||||||||
| WBPaper00050742 | |||||||||
| WBPaper00053000 | |||||||||
| Method | Substitution_allele |
