WormBase Tree Display for Variation: WBVar00090673

WBVar00090673 Evidence: Paper_evidence: WBPaper00025096
  Name: Public_name: n3247
  Sequence_details: Mapping_target: H13N06
    Type_of_mutation: Deletion
    SeqStatus: Pending_curation
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00027363
    Laboratory: MT
    Status: Live
  Affects: Gene: WBGene00006541
  Description: Phenotype (16)
    Phenotype_not_observed: WBPhenotype:0001101 Paper_evidence: WBPaper00038382
        Curator_confirmed: WBPerson712
        Remark: tbh-1 mutants do not block clozapine-induced egg laying. Paper_evidence: WBPaper00038382
            Curator_confirmed: WBPerson712
        Affected_by: Molecule: WBMol:00003634 Paper_evidence: WBPaper00038382
              Curator_confirmed: WBPerson712
      WBPhenotype:0001765 Paper_evidence: WBPaper00031936
        Curator_confirmed: WBPerson2021
        Remark: Mutants defective in the synthesis and reception of nonessential excitatory neurotransmitters respond normally to CO2 Paper_evidence: WBPaper00031936
            Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000057 PATO:0000460 Paper_evidence: WBPaper00031936
                Curator_confirmed: WBPerson2021
        Phenotype_assay: Treatment: 10% CO2 Paper_evidence: WBPaper00031936
              Curator_confirmed: WBPerson2021
  Reference: WBPaper00038382
    WBPaper00043908
    WBPaper00031936
    WBPaper00031241
    WBPaper00045634
    WBPaper00065715
  Remark: The tbh-1(n3247) mutant allele removes 791 bp, deleting parts of exons 6 and 7, and causes a frameshift that leads to a premature truncation of the TBH-1 protein Paper_evidence: WBPaper00025096
  Method: Deletion_allele