WormBase Tree Display for Variation: WBVar00091798

WBVar00091798 Name: Public_name: ok511
    HGVSg: CHROMOSOME_II:g.11966426_11967166delinsCTCCAACAAGCTACTGC
  Sequence_details: SMap: S_parent: Sequence: W03C9
    Flanking_sequences: agtttttttacagaaaaaatgtgatttttc aattcctccaacaagctactgcatgtcctt
    Mapping_target: W03C9
    Type_of_mutation: Insertion: CTCCAACAAGCTACTGC
      Deletion
    PCR_product: ok511_external
      ok511_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00035667
    Laboratory: RB
    Person: WBPerson46
    KO_consortium_allele
    Status: Live
  Affects: Gene: WBGene00012221
      WBGene00004271
    Transcript: W03C9.3.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,5_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        Intron_number: 2-4/6
        Exon_number: 1-4/7
      W03C9.5.1 VEP_consequence: 3_prime_UTR_variant
        VEP_impact: MODIFIER
        cDNA_position: 285-?
        Exon_number: 5/5
  Isolation: Mutagen: UV/TMP
  Genetics: Mapping_data: In_multi_point: 4619
  Description: Phenotype: WBPhenotype:0000736 Paper_evidence: WBPaper00040312
        Curator_confirmed: WBPerson712
        Remark: The disappearance of MitoTracker Red-labeled sperm mitochondria was inhibited in rab-7(ok511) null mutant embryos. Paper_evidence: WBPaper00040312
            Curator_confirmed: WBPerson712
      WBPhenotype:0001135 Paper_evidence: WBPaper00040312
        Curator_confirmed: WBPerson712
        Remark: Paternal mitochondria persisted. Paper_evidence: WBPaper00040312
            Curator_confirmed: WBPerson712
      WBPhenotype:0001846 Paper_evidence: WBPaper00031805
        Curator_confirmed: WBPerson2021
        Remark: In rab-7(ok511) mutant worms, corpses were arrested in AO-negative phagosomes Paper_evidence: WBPaper00031805
            Curator_confirmed: WBPerson2021
    Phenotype_not_observed: WBPhenotype:0000706 Paper_evidence: WBPaper00025094
        Curator_confirmed: WBPerson2021
        Remark: Mutations did not result in Glo phenotypes Paper_evidence: WBPaper00025094
            Curator_confirmed: WBPerson2021
        Variation_effect: Null: Paper_evidence: WBPaper00025094
            Curator_confirmed: WBPerson2021
        Phenotype_assay: Treatment: Staining with LysoTracker Red and acridine orange Paper_evidence: WBPaper00025094
              Curator_confirmed: WBPerson2021
  Reference: WBPaper00040312
    WBPaper00031805
    WBPaper00025094
  Remark: Sequenced by the C. elegans Gene Knockout Consortium Paper_evidence: WBPaper00041807
  Method: KO_consortium_allele