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WormBase Tree Display for Variation: WBVar00091940

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Name Class

WBVar00091940NamePublic_nameok656
Other_nameT07C4.2.1:c.182_829del
T07C4.2.2:c.182_829del
CE36891:p.Pro61_Ter277delinsGln
HGVSgCHROMOSOME_III:g.10347765_10349482del
Sequence_detailsSMapS_parentSequenceT07C4
Flanking_sequencesagctctacgctatgatgcttcatattgagcaattcccatttggacttccatgcttctccc
Mapping_targetT07C4
Type_of_mutationDeletion
PCR_productok656_external
ok656_internal
SeqStatusSequenced
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
StrainWBStrain00031544
LaboratoryRB
PersonWBPerson46
KO_consortium_allele
StatusLive
AffectsGeneWBGene00006545
TranscriptT07C4.2.1 (11)
T07C4.2.2 (11)
InteractorWBInteraction000007723
WBInteraction000052316
WBInteraction000052317
WBInteraction000521960
WBInteraction000521963
IsolationMutagenUV/TMP
GeneticsMapping_dataIn_multi_point4790
DescriptionPhenotypeWBPhenotype:0000035Paper_evidenceWBPaper00040526
Curator_confirmedWBPerson712
RemarkUpregulated expression of tbx-9::gfp predicted the phenotypic outcome of the tbx-8 mutation. | The daf-21::mCherry reporter predicted the tbx-8(ok656) mutation morphological outcome.Paper_evidenceWBPaper00040526
Curator_confirmedWBPerson712
PenetranceIncompletePaper_evidenceWBPaper00040526
Curator_confirmedWBPerson712
Variation_effectNullPaper_evidenceWBPaper00040526
Curator_confirmedWBPerson712
WBPhenotype:0000050Paper_evidenceWBPaper00025190
Curator_confirmedWBPerson712
PenetranceLowPaper_evidenceWBPaper00025190
Curator_confirmedWBPerson712
WBPhenotype:0000189Paper_evidenceWBPaper00006477
Curator_confirmedWBPerson712
RemarkLateral hypodermal cells are disorganized as assayed by the pattern of AJM::GFP expression in hypodermal cells in 48% (n=54) embryos scored.Paper_evidenceWBPaper00006477
Curator_confirmedWBPerson712
EQ_annotationsAnatomy_termWBbt:0005733PATO:0000460Paper_evidenceWBPaper00006477
Curator_confirmedWBPerson712
Life_stageWBls:0000018PATO:0000460Paper_evidenceWBPaper00006477
Curator_confirmedWBPerson712
Phenotype_assayGenotypeAJM::GFPPaper_evidenceWBPaper00006477
Curator_confirmedWBPerson712
WBPhenotype:0000351Paper_evidenceWBPaper00006477
Curator_confirmedWBPerson712
Remark1.6% (n=1071)eggs were unable to hatch, compared with 0.6% dpy-17/+ ok656/+ (n=574)and 1.1% dpy-17/+ (n=284) unable to hatch.Paper_evidenceWBPaper00006477
Curator_confirmedWBPerson712
PenetranceLowPaper_evidenceWBPaper00006477
Curator_confirmedWBPerson712
EQ_annotationsLife_stageWBls:0000003PATO:0000460Paper_evidenceWBPaper00006477
Curator_confirmedWBPerson712
WBPhenotype:0000535Paper_evidenceWBPaper00006477
Curator_confirmedWBPerson712
Remark3.5% of animals exhibited disorganized body morphology in < half their body length. 0.7% animals exhibited disorganized body morphology > half their body length (n=1071).Paper_evidenceWBPaper00006477
Curator_confirmedWBPerson712
RecessivePaper_evidenceWBPaper00006477
Curator_confirmedWBPerson712
WBPhenotype:0000793Paper_evidenceWBPaper00025190
Curator_confirmedWBPerson712
PenetranceLowPaper_evidenceWBPaper00025190
Curator_confirmedWBPerson712
WBPhenotype:0001236Paper_evidenceWBPaper00040526
Curator_confirmedWBPerson712
RemarkAnimals exhibited upregulated expression of tbx-9::gfp.Paper_evidenceWBPaper00040526
Curator_confirmedWBPerson712
PenetranceIncompletePaper_evidenceWBPaper00040526
Curator_confirmedWBPerson712
Variation_effectNullPaper_evidenceWBPaper00040526
Curator_confirmedWBPerson712
ReferenceWBPaper00040526
WBPaper00018977
WBPaper00025190
WBPaper00006477
RemarkSequenced by the C. elegans Gene Knockout ConsortiumPaper_evidenceWBPaper00041807
MethodKO_consortium_allele