Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Variation: WBVar00092131

expand all nodes | collapse all nodes | view schema

Name Class

WBVar00092131NamePublic_nameok856
Other_nameC05A9.1b.1:c.1984_2770del
C05A9.1a.1:c.2260_3046del
CE43182:p.Lys662SerfsTer6
CE43003:p.Lys754SerfsTer6
HGVSgCHROMOSOME_X:g.10855196_10856123del
Sequence_detailsSMapS_parentSequenceC05A9
Flanking_sequencescaccatccaaaatcattttgtctgagcgctttctgctgttttaccgaagaaataatattg
Mapping_targetC05A9
Type_of_mutationDeletion
PCR_productOK856_external
OK856_internal
SeqStatusSequenced
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
StrainWBStrain00031670
LaboratoryRB
PersonWBPerson46
KO_consortium_allele
StatusLive
AffectsGeneWBGene00003999
TranscriptC05A9.1b.1 (11)
C05A9.1a.1 (11)
IsolationMutagenUV/TMP
DescriptionPhenotypeWBPhenotype:0000593Paper_evidenceWBPaper00031023
Curator_confirmedWBPerson2987
RemarkAt concentrations of copper sulfate in which development of wild-type animals was impaired, the proportions of pgp-5(ok856) animals with developmental delay were significantly higher (Figure 2B).Paper_evidenceWBPaper00031023
Curator_confirmedWBPerson2987
Affected_byMoleculeWBMol:00002862Paper_evidenceWBPaper00031023
Curator_confirmedWBPerson2987
WBPhenotype:0001271Paper_evidenceWBPaper00031023
Curator_confirmedWBPerson2987
Remarkpgp-5(ok856) mutant animals exhibited reduced survival at 15 degrees Celsius in the presence of pathogenic Pseudomonas aeruginosa strain PA14 and Salmonella typhimurium strain SL1344, compared to wild type controls (Figure 2C, 2D).Paper_evidenceWBPaper00031023
Curator_confirmedWBPerson2987
Phenotype_assayTemperature15Paper_evidenceWBPaper00031023
Curator_confirmedWBPerson2987
WBPhenotype:0001655Paper_evidenceWBPaper00031023
Curator_confirmedWBPerson2987
RemarkAt concentrations of cadmium chloride in which development of wild-type animals was impaired, the proportions of pgp-5(ok856) animals with developmental delay were significantly higher (Figure 2A).Paper_evidenceWBPaper00031023
Curator_confirmedWBPerson2987
Affected_byMoleculeWBMol:00003022Paper_evidenceWBPaper00031023
Curator_confirmedWBPerson2987
Phenotype_not_observedWBPhenotype:0000031Paper_evidenceWBPaper00031023
Curator_confirmedWBPerson2987
RemarkFigure 2A, 2BPaper_evidenceWBPaper00031023
Curator_confirmedWBPerson2987
WBPhenotype:0000039Paper_evidenceWBPaper00031023
Curator_confirmedWBPerson2987
RemarkThe lifespan of the pgp-5(ok856) mutants was not different from that of N2 (wild type) animals at 25 degrees Celsius (data not shown) nor at 15 degrees Celsius (Figure S3C).Paper_evidenceWBPaper00031023
Curator_confirmedWBPerson2987
WBPhenotype:0000486Paper_evidenceWBPaper00031023
Curator_confirmedWBPerson2987
Remarkpgp-5(ok856) mutant animals responded normally to colchicine, compared to wild type controls (Figure S3A)Paper_evidenceWBPaper00031023
Curator_confirmedWBPerson2987
Affected_byMoleculeWBMol:00003637Paper_evidenceWBPaper00031023
Curator_confirmedWBPerson2987
WBPhenotype:0001208Paper_evidenceWBPaper00027644
Curator_confirmedWBPerson557
RemarkAnimals were not resistant to RNAi as assayed on either pop-1 RNAi or unc-22 RNAi.Paper_evidenceWBPaper00027644
Curator_confirmedWBPerson557
Phenotype_assayTreatmentAnimals reared on both pop-1 and unc-22 feeding plates at 15, 20, 25, and 26C.Paper_evidenceWBPaper00027644
Curator_confirmedWBPerson557
WBPhenotype:0002218Paper_evidenceWBPaper00031023
Curator_confirmedWBPerson2987
Remarkpgp-5(ok856) mutant animals responded normally to arsenite, compared to wild type controls (Figure S3A)Paper_evidenceWBPaper00031023
Curator_confirmedWBPerson2987
Affected_byMoleculeWBMol:00004596Paper_evidenceWBPaper00031023
Curator_confirmedWBPerson2987
ReferenceWBPaper00027644
WBPaper00031023
RemarkSequenced by the C. elegans Gene Knockout ConsortiumPaper_evidenceWBPaper00041807
MethodKO_consortium_allele