WormBase Tree Display for Variation: WBVar00094146

WBVar00094146 Name: Public_name: ok3065
    Other_name: Y23B4A.2.2:c.-6+87_165-18del
    HGVSg: CHROMOSOME_X:g.5919506_5920103del
  Sequence_details: SMap: S_parent: Sequence: Y23B4A
    Flanking_sequences: ttccttttctgtcttttattaatttccttt aaaattttgtttttcagtaacaattccgaa
    Mapping_target: Y23B4A
    Type_of_mutation: Deletion
    PCR_product: ok3065_external
      ok3065_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00032943
    Laboratory: RB
    Person: WBPerson46
    KO_consortium_allele
    Status: Live
  Affects: Gene: WBGene00021268
    Transcript: Y23B4A.2.2 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,5_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: Y23B4A.2.2:c.-6+87_165-18del
        Intron_number: 1-4/5
        Exon_number: 2-4/6
      Y23B4A.2.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,5_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        Intron_number: 2-3/4
        Exon_number: 1-3/5
  Isolation: Mutagen: EMS
  Description: Phenotype: WBPhenotype:0002598 Paper_evidence: WBPaper00059641
        Curator_confirmed: WBPerson10038
        Remark: Quote from paper: "We first tested gustatory aversive learning of capa-1 mutants (Fig.4c) in the quadrant assay (Fig.5a). As expected, capa-1 animals were still attracted to NaCl after experiencing it in absence of food (Fig.5a). This learning defect did not result from general defects in salt chemotaxis behavior or in responses to osmotic stimuli (Supplementary Fig. 1a-c). Furthermore, capa-1 animals showed normal salt chemotaxis behavior when NaCl was paired with food but were defective in associating salt with different aversive experiences (Supplementary Fig. 1d, e)." Paper_evidence: WBPaper00059641
            Curator_confirmed: WBPerson10038
        Affected_by: Molecule: WBMol:00003571 Paper_evidence: WBPaper00059641
              Curator_confirmed: WBPerson10038
  Reference: WBPaper00059641
  Remark: Sequenced by the C. elegans Gene Knockout Consortium Paper_evidence: WBPaper00041807
  Method: KO_consortium_allele