WormBase Tree Display for Variation: WBVar00094890

WBVar00094890 Evidence: Paper_evidence: WBPaper00030973
    Person_evidence: WBPerson260
  Name: Public_name: ot177
    Other_name (19)
    HGVSg: CHROMOSOME_V:g.9846753G>A
  Sequence_details: SMap: S_parent: Sequence: R07B5
    Flanking_sequences: tatccatacaccaactatcctaatatttgg agcccccgtatcagaattatccatacaacc
    Mapping_target: R07B5
    Type_of_mutation: Substitution: c t
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00029547
    Laboratory: OH
    Status: Live
  Affects: Gene: WBGene00045419
    Transcript (11)
  Genetics: Map: V
    Interpolated_map_position: V 2.20081
  Description: Phenotype: WBPhenotype:0001660 Paper_evidence: WBPaper00030973
          WBPaper00032078
          WBPaper00036201
        Curator_confirmed: WBPerson2021
          WBPerson712
        Remark: ASE asymmetry is disrupted. 2 ASER Paper_evidence: WBPaper00030973
            Curator_confirmed: WBPerson2021
          56% (n=36) class II lsy phenotype = "2 ASER" (Sarin et al., 2007), scored with either ASEL marker lim-6::gfp (otIs114), which is lost in ASEL; or with ASER marker gcy- 5::gfp (otIs186), which is ectopically expressed in ASEL. Animals were scored as late larva or as adult. Wild type exhibits 0% lsy phenotype. Paper_evidence: WBPaper00032078
            Curator_confirmed: WBPerson712
          Identified in WGS (Whole Genome Sequencing) analysis. Paper_evidence: WBPaper00036201
            Curator_confirmed: WBPerson712
        Penetrance: Incomplete: Paper_evidence: WBPaper00030973
              Curator_confirmed: WBPerson2021
          Range: 42 50 Paper_evidence: WBPaper00030973
                Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00030973
            WBPaper00032078
          Curator_confirmed: WBPerson2021
            WBPerson712
        EQ_annotations: Anatomy_term: WBbt:0005663 PATO:0000460 Paper_evidence: WBPaper00030973
                Curator_confirmed: WBPerson2021
        Phenotype_assay: Temperature: 25C Paper_evidence: WBPaper00030973
              Curator_confirmed: WBPerson2021
          Genotype: otIs114 [lim-6p::GFP], ntIs1 [ gcy-5p::GFP] Paper_evidence: WBPaper00030973
              Curator_confirmed: WBPerson2021
            lim-6::gfp (otIs114), gcy- 5::gfp (otIs186) Paper_evidence: WBPaper00032078
              Curator_confirmed: WBPerson712
            otIs114 Paper_evidence: WBPaper00036201
              Curator_confirmed: WBPerson712
  Reference: WBPaper00030973
    WBPaper00032078
    WBPaper00036201
  Method: Substitution_allele