WormBase Tree Display for Variation: WBVar00095089

WBVar00095089 Evidence: Paper_evidence: WBPaper00033006
  Name: Public_name: oz159
    Other_name: C37C3.6a.2:c.*1822C>T
      C37C3.6b.1:c.5263C>T
      C37C3.7.1:c.*70G>A
      C37C3.6a.1:c.*1822C>T
      CE17536:p.Gln1755Ter
    HGVSg: CHROMOSOME_V:g.7835299C>T
  Sequence_details: SMap: S_parent: Sequence: C37C3
    Flanking_sequences: aaatctttcagattcgactctgaaaagtct aatgtgtaaccttcatgtattctggatgta
    Mapping_target: C37C3
    Type_of_mutation: Substitution: c t Paper_evidence: WBPaper00033006
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Laboratory: BS
    Status: Live
  Affects: Gene: WBGene00016499
      WBGene00003242
    Transcript: C37C3.7.1 VEP_consequence: 3_prime_UTR_variant
        VEP_impact: MODIFIER
        HGVSc: C37C3.7.1:c.*70G>A
        cDNA_position: 1205
        Exon_number: 8/8
      C37C3.6b.1 VEP_consequence: stop_gained
        VEP_impact: HIGH
        HGVSc: C37C3.6b.1:c.5263C>T
        HGVSp: CE17536:p.Gln1755Ter
        cDNA_position: 5335
        CDS_position: 5263
        Protein_position: 1755
        Exon_number: 16/20
        Codon_change: Caa/Taa
        Amino_acid_change: Q/*
      C37C3.6a.2 VEP_consequence: 3_prime_UTR_variant
        VEP_impact: MODIFIER
        HGVSc: C37C3.6a.2:c.*1822C>T
        cDNA_position: 6509
        Exon_number: 15/18
      C37C3.6a.1 VEP_consequence: 3_prime_UTR_variant
        VEP_impact: MODIFIER
        HGVSc: C37C3.6a.1:c.*1822C>T
        cDNA_position: 6567
        Exon_number: 15/18
  Genetics: Interpolated_map_position: V 0.91196
  Description: Phenotype: WBPhenotype:0000195 Paper_evidence: WBPaper00033006
        Curator_confirmed: WBPerson2021
        Remark: DTC migration is extremely slow relative to the wild type, resulting in foreshortened gonad arms Paper_evidence: WBPaper00033006
            Curator_confirmed: WBPerson2021
        Penetrance: Complete: Paper_evidence: WBPaper00033006
              Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00033006
          Curator_confirmed: WBPerson2021
        EQ_annotations: Anatomy_term: WBbt:0006865 PATO:0000460 Paper_evidence: WBPaper00033006
                Curator_confirmed: WBPerson2021
      WBPhenotype:0000688 Paper_evidence: WBPaper00033006
        Curator_confirmed: WBPerson2021
        Remark: mig-6(l) mutant animals are completely sterile Paper_evidence: WBPaper00033006
            Curator_confirmed: WBPerson2021
        Penetrance: Complete: Paper_evidence: WBPaper00033006
              Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00033006
          Curator_confirmed: WBPerson2021
  Reference: WBPaper00033006
  Method: Substitution_allele