WormBase Tree Display for Variation: WBVar00145123

WBVar00145123 Evidence: Paper_evidence: WBPaper00005708
  Name: Public_name: eh10
    Other_name: C37A2.4b.1:c.178_1201del
      CE33761:p.Gln60CysfsTer79
      C37A2.4a.1:c.178_1210del
      CE24832:p.Gln60CysfsTer79
    HGVSg: CHROMOSOME_I:g.6781087_6783455del
  Sequence_details: SMap: S_parent: Sequence: C37A2
    Flanking_sequences: cgaaatacccgaaattcgagcgttggaagt tgtgtaaaattctcgattttctgctatttg
    Mapping_target: C37A2
    Type_of_mutation: Deletion
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00023600
    Laboratory: HX
    Status: Live
  Affects: Gene: WBGene00022955
      WBGene00000871
    Transcript: C37A2.4a.1 (11)
      C37A2.4b.1 (11)
      C37A2.t1 VEP_consequence: transcript_ablation
        VEP_impact: HIGH
        Exon_number: 1/1
    Interactor: WBInteraction000517294
  Genetics: Interpolated_map_position: I 1.31698
  Description: Phenotype: WBPhenotype:0000239 Paper_evidence: WBPaper00035599
        Curator_confirmed: WBPerson2021
        Remark: Loss of the second round of vulval cell division Paper_evidence: WBPaper00035599
            Curator_confirmed: WBPerson2021
      WBPhenotype:0000318 Paper_evidence: WBPaper00035599
        Curator_confirmed: WBPerson2021
        Remark: The time delay between the first and the second vulval division is abnormally long, so that the second (terminal) division of cye-1 (eh10) occurs at about the same time as the third (terminal) division of the wild type. Paper_evidence: WBPaper00035599
            Curator_confirmed: WBPerson2021
      WBPhenotype:0000697 Paper_evidence: WBPaper00038281
        Curator_confirmed: WBPerson712
        Remark: Rescued by qIs134[Pcye-1::CYE-1; Psur-5::GFP]. Paper_evidence: WBPaper00038281
            Curator_confirmed: WBPerson712
      WBPhenotype:0001927 Paper_evidence: WBPaper00029347
        Curator_confirmed: WBPerson557
        Penetrance: Incomplete: 36 percent showed the phenotype. Paper_evidence: WBPaper00029347
              Curator_confirmed: WBPerson557
        Phenotype_assay: Genotype: lag-2::GFP Paper_evidence: WBPaper00029347
              Curator_confirmed: WBPerson557
      WBPhenotype:0001928 Paper_evidence: WBPaper00029347
        Curator_confirmed: WBPerson557
        Penetrance: Incomplete: 36 percent showed the phenotype. Paper_evidence: WBPaper00029347
              Curator_confirmed: WBPerson557
  Reference: WBPaper00038281
    WBPaper00005708
    WBPaper00029347
    WBPaper00035599
    WBPaper00044900
  Method: Deletion_allele