WormBase Tree Display for Variation: WBVar00145606

WBVar00145606 Evidence: Paper_evidence: WBPaper00006526
  Name: Public_name: gk199
    HGVSg: CHROMOSOME_V:g.13193198_13193632del
  Sequence_details: SMap: S_parent: Sequence: F57B1
    Flanking_sequences: aacaacagccataagagtacgtttaaactg ttgtttcaattaaaataattatgaattaat
    Mapping_target: F57B1
    Type_of_mutation: Deletion
    PCR_product: gk199_external
      gk199_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00035653
    Laboratory: VC
    Person: WBPerson427
    KO_consortium_allele
    Status: Live
  Affects: Gene: WBGene00006311
    Transcript: F57B1.2.1 VEP_consequence: coding_sequence_variant,5_prime_UTR_variant
        VEP_impact: MODIFIER
        cDNA_position: ?-341
        CDS_position: ?-330
        Protein_position: ?-110
        Exon_number: 1-2/7
  Isolation: Mutagen: TMP/UV
  Genetics: Mapping_data: In_multi_point: 4713
  Description: Phenotype: WBPhenotype:0000188 Paper_evidence: WBPaper00006526
        Curator_confirmed: WBPerson2021
        Remark: Gonad size is significantly reduced in adults Paper_evidence: WBPaper00006526
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00006526
          Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000041 PATO:0000460 Paper_evidence: WBPaper00006526
                Curator_confirmed: WBPerson2021
      WBPhenotype:0000395 Paper_evidence: WBPaper00006526
        Curator_confirmed: WBPerson2021
        Remark: Animals lack mature gametes Paper_evidence: WBPaper00006526
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00006526
          Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000041 PATO:0000460 Paper_evidence: WBPaper00006526
                Curator_confirmed: WBPerson2021
      WBPhenotype:0000684 Paper_evidence: WBPaper00006526
        Curator_confirmed: WBPerson2021
        Remark: Animals have reduced numbers of germ cells Paper_evidence: WBPaper00006526
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00006526
          Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000041 PATO:0000460 Paper_evidence: WBPaper00006526
                Curator_confirmed: WBPerson2021
      WBPhenotype:0000688 Paper_evidence: WBPaper00006526
        Curator_confirmed: WBPerson2021
        Remark: gk199 progeny all developed into adult animals that were sterile Paper_evidence: WBPaper00006526
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00006526
          Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000041 PATO:0000460 Paper_evidence: WBPaper00006526
                Curator_confirmed: WBPerson2021
    Phenotype_not_observed: WBPhenotype:0000436 Paper_evidence: WBPaper00006526
        Curator_confirmed: WBPerson2021
        Remark: No effect on the localization of Ce-lamin, UNC-84, FG-nucleoporins, Ce-emerin, or Ce-MAN1 in germ-line cells Paper_evidence: WBPaper00006526
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00006526
          Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000041 PATO:0000460 Paper_evidence: WBPaper00006526
                Curator_confirmed: WBPerson2021
        Phenotype_assay: Treatment: Antibody staining to lamin, UNC-84, emerin, MAN-1 and FG nucleoporins Paper_evidence: WBPaper00006526
              Curator_confirmed: WBPerson2021
  Reference: WBPaper00006526
  Remark: Sequenced by the C. elegans Gene Knockout Consortium Paper_evidence: WBPaper00041807
  Method: KO_consortium_allele