WormBase Tree Display for Variation: WBVar00145621

WBVar00145621 Name: Public_name: gk214
    Other_name: F48F7.1a.1:c.23_210+32delinsCTGATATTCTCTG
      F48F7.1b.1:c.86_273+32delinsCTGATATTCTCTG
      F48F7.1a.3:c.23_210+32delinsCTGATATTCTCTG
      F48F7.1a.2:c.23_210+32delinsCTGATATTCTCTG
    HGVSg: CHROMOSOME_X:g.13951313_13951532delinsCTGATATTCTCTG
  Sequence_details: SMap: S_parent: Sequence: K02B9
    Flanking_sequences: acgacccaatgtccggcgggccgcaatatt acatctgatattatcttgttattagtttgt
    Mapping_target: K02B9
    Type_of_mutation: Insertion: CTGATATTCTCTG
      Deletion
    PCR_product: gk214_external
      gk214_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00033317
      WBStrain00035775
    Laboratory: VC
    Person: WBPerson427
    KO_consortium_allele
    Status: Live
  Affects: Gene: WBGene00000105
    Transcript: F48F7.1b.1 VEP_consequence: splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: F48F7.1b.1:c.86_273+32delinsCTGATATTCTCTG
        cDNA_position: 86-?
        CDS_position: 86-?
        Protein_position: 29-?
        Intron_number: 2/6
        Exon_number: 2/7
      F48F7.1a.2 VEP_consequence: splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: F48F7.1a.2:c.23_210+32delinsCTGATATTCTCTG
        cDNA_position: 465-?
        CDS_position: 23-?
        Protein_position: 8-?
        Intron_number: 3/8
        Exon_number: 3/9
      F48F7.1a.1 VEP_consequence: splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: F48F7.1a.1:c.23_210+32delinsCTGATATTCTCTG
        cDNA_position: 52-?
        CDS_position: 23-?
        Protein_position: 8-?
        Intron_number: 2/7
        Exon_number: 2/8
      F48F7.1a.3 VEP_consequence: splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: F48F7.1a.3:c.23_210+32delinsCTGATATTCTCTG
        cDNA_position: 1743-?
        CDS_position: 23-?
        Protein_position: 8-?
        Intron_number: 2/7
        Exon_number: 2/8
    Interactor (21)
  Isolation: Mutagen: UV/TMP
  Genetics: Mapping_data: In_multi_point: 4153
  Description: Phenotype (13)
    Phenotype_not_observed: WBPhenotype:0001371 Paper_evidence: WBPaper00029211
        Curator_confirmed: WBPerson712
        Remark: Both wild-type extract and alg-1(gk214) (result not shown) are capable of forming a ribonucleoprotein (RNP) complex with the pre-let-7. Paper_evidence: WBPaper00029211
            Curator_confirmed: WBPerson712
      WBPhenotype:0002155 Paper_evidence: WBPaper00029211
        Curator_confirmed: WBPerson712
        Remark: alg-1(gk214) extracts show that pre-let-7 is processed normally. Paper_evidence: WBPaper00029211
            Curator_confirmed: WBPerson712
  Reference (11)
  Remark: Sequenced by the C. elegans Gene Knockout Consortium Paper_evidence: WBPaper00041807
  Method: KO_consortium_allele