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WormBase Tree Display for Variation: WBVar00146701

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Name Class

WBVar00146701EvidencePaper_evidenceWBPaper00014737
NamePublic_nameh842
Sequence_detailsSeqStatusPending_curation
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
StrainWBStrain00023892
LaboratoryKR
StatusLive
AffectsGeneWBGene00002735
GeneticsMapping_dataIn_pos_neg_data5426
5427
5428
5429
5430
6179
6591
DescriptionPhenotypeWBPhenotype:0000688Paper_evidenceWBPaper00003985
WBPaper00002829
Person_evidenceWBPerson261
Curator_confirmedWBPerson712
Remarksterile adult, very few germ line nuclei, no oocytes or sperm.Person_evidenceWBPerson261
Curator_confirmedWBPerson712
sterile adult mutants had a normal life-span of two to three weeks and grew to the expected size for Unc-13 adults (0.6+/-0.8 mm), gonadal cells became necrotic and began to break down soon after the animal reached adulthoodPaper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
RecessivePaper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
EQ_annotationsLife_stageWBls:0000041PATO:0000460Paper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
Phenotype_assayGenotypedpy-5 unc-13; sDp2Paper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
WBPhenotype:0000774Paper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
RemarkThese mutants arrested as adults and formed gonads, but had defects in germ cell proliferation, or in the formation of mature gametes. germ cells in the gonad showed less differentiation than those in let-544(h692).Paper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
RecessivePaper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
EQ_annotationsLife_stageWBls:0000041PATO:0000460Paper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
Phenotype_assayGenotypedpy-5 unc-13; sDp2Paper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
WBPhenotype:0000823Paper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
Remarkthere were a reduced number of germ cells in the gonadPaper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
RecessivePaper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
EQ_annotationsLife_stageWBls:0000041PATO:0000460Paper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
Phenotype_assayGenotypedpy-5 unc-13; sDp2Paper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
Phenotype_not_observedWBPhenotype:0000670Paper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
Remarknone of the sterile mutants were rescued by wild-type sperm, therefore none of them had defects in spermatogenesis alone. spermatogenesis occurred, as revealed by DAPI stainingPaper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
RecessivePaper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
EQ_annotationsLife_stageWBls:0000041PATO:0000460Paper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
Phenotype_assayGenotypedpy-5 unc-13; sDp2Paper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
WBPhenotype:0000683Paper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
Remarkfailed to produce oocytes, spermatogenesis occursPaper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
RecessivePaper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
EQ_annotationsLife_stageWBls:0000041PATO:0000460Paper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
Phenotype_assayGenotypedpy-5 unc-13; sDp2Paper_evidenceWBPaper00002829
Curator_confirmedWBPerson712
ReferenceWBPaper00014737
WBPaper00002829
WBPaper00003985
MethodAllele