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WormBase Tree Display for Variation: WBVar00241486

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Name Class

WBVar00241486NamePublic_namera515
Sequence_detailsSeqStatusPending_curation
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
StrainWBStrain00005884
LaboratoryDM
StatusLive
AffectsGeneWBGene00006787
InteractorWBInteraction000538527
WBInteraction000538531
DescriptionPhenotype_not_observedWBPhenotype:0000195Paper_evidenceWBPaper00005809
Curator_confirmedWBPerson2987
Remark"The unc-52(ra515) and unc-52(gk3) alleles result from deletions of exons 15 through 18 encoding four Domain IV Ig repeats, or exons 28 through 37 encoding the C-terminal Domain V of UNC-52, respectively (Mullen et al., 1999)... DTC migrations are normal in these strains, and the frequency of DTC migration defects in double mutants of unc-52(ra515); unc-5(e152) and unc-52(gk3); unc-5(e152) are not significantly different from unc-5(e152) alone (P > 0.1; Table 1)."Paper_evidenceWBPaper00005809
Curator_confirmedWBPerson2987
EQ_annotationsAnatomy_termWBbt:0006865PATO:0000460Paper_evidenceWBPaper00005809
Curator_confirmedWBPerson2987
GO_termGO:0016477PATO:0000460Paper_evidenceWBPaper00005809
Curator_confirmedWBPerson2987
WBPhenotype:0000643Paper_evidenceWBPaper00005809
Curator_confirmedWBPerson2987
Remark"The unc-52(ra515) and unc-52(gk3) alleles result from deletions of exons 15 through 18 encoding four Domain IV Ig repeats, or exons 28 through 37 encoding the C-terminal Domain V of UNC-52, respectively (Mullen et al., 1999). Neither of these alleles exhibits the severe Unc or gonadal rupture phenotypes of the class I viable unc-52 alleles."Paper_evidenceWBPaper00005809
Curator_confirmedWBPerson2987
WBPhenotype:0000691Paper_evidenceWBPaper00005809
Curator_confirmedWBPerson2987
Remark"The unc-52(ra515) and unc-52(gk3) alleles result from deletions of exons 15 through 18 encoding four Domain IV Ig repeats, or exons 28 through 37 encoding the C-terminal Domain V of UNC-52, respectively (Mullen et al., 1999). Neither of these alleles exhibits the severe Unc or gonadal rupture phenotypes of the class I viable unc-52 alleles."Paper_evidenceWBPaper00005809
Curator_confirmedWBPerson2987
ReferenceWBPaper00005809
MethodAllele