WormBase Tree Display for Variation: WBVar00241486
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WBVar00241486 | Name | Public_name | ra515 | ||||||
---|---|---|---|---|---|---|---|---|---|
Sequence_details | SeqStatus | Pending_curation | |||||||
Variation_type | Allele | ||||||||
Origin | Species | Caenorhabditis elegans | |||||||
Strain | WBStrain00005884 | ||||||||
Laboratory | DM | ||||||||
Status | Live | ||||||||
Affects | Gene | WBGene00006787 | |||||||
Interactor | WBInteraction000538527 | ||||||||
WBInteraction000538531 | |||||||||
Description | Phenotype_not_observed | WBPhenotype:0000195 | Paper_evidence | WBPaper00005809 | |||||
Curator_confirmed | WBPerson2987 | ||||||||
Remark | "The unc-52(ra515) and unc-52(gk3) alleles result from deletions of exons 15 through 18 encoding four Domain IV Ig repeats, or exons 28 through 37 encoding the C-terminal Domain V of UNC-52, respectively (Mullen et al., 1999)... DTC migrations are normal in these strains, and the frequency of DTC migration defects in double mutants of unc-52(ra515); unc-5(e152) and unc-52(gk3); unc-5(e152) are not significantly different from unc-5(e152) alone (P > 0.1; Table 1)." | Paper_evidence | WBPaper00005809 | ||||||
Curator_confirmed | WBPerson2987 | ||||||||
EQ_annotations | Anatomy_term | WBbt:0006865 | PATO:0000460 | Paper_evidence | WBPaper00005809 | ||||
Curator_confirmed | WBPerson2987 | ||||||||
GO_term | GO:0016477 | PATO:0000460 | Paper_evidence | WBPaper00005809 | |||||
Curator_confirmed | WBPerson2987 | ||||||||
WBPhenotype:0000643 | Paper_evidence | WBPaper00005809 | |||||||
Curator_confirmed | WBPerson2987 | ||||||||
Remark | "The unc-52(ra515) and unc-52(gk3) alleles result from deletions of exons 15 through 18 encoding four Domain IV Ig repeats, or exons 28 through 37 encoding the C-terminal Domain V of UNC-52, respectively (Mullen et al., 1999). Neither of these alleles exhibits the severe Unc or gonadal rupture phenotypes of the class I viable unc-52 alleles." | Paper_evidence | WBPaper00005809 | ||||||
Curator_confirmed | WBPerson2987 | ||||||||
WBPhenotype:0000691 | Paper_evidence | WBPaper00005809 | |||||||
Curator_confirmed | WBPerson2987 | ||||||||
Remark | "The unc-52(ra515) and unc-52(gk3) alleles result from deletions of exons 15 through 18 encoding four Domain IV Ig repeats, or exons 28 through 37 encoding the C-terminal Domain V of UNC-52, respectively (Mullen et al., 1999). Neither of these alleles exhibits the severe Unc or gonadal rupture phenotypes of the class I viable unc-52 alleles." | Paper_evidence | WBPaper00005809 | ||||||
Curator_confirmed | WBPerson2987 | ||||||||
Reference | WBPaper00005809 | ||||||||
Method | Allele |