WormBase Tree Display for Variation: WBVar00242631

WBVar00242631 Evidence: Paper_evidence: WBPaper00031959
  Name: Public_name: sa1205
  Sequence_details: Mapping_target: F36F2
    SeqStatus: Pending_curation
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Laboratory: JT
    Status: Live
  Affects: Gene: WBGene00006525
  Description: Phenotype: WBPhenotype:0000254 Paper_evidence: WBPaper00031959
        Curator_confirmed: WBPerson712
        Remark: Animals were completely defective in NaCl chemotaxis but not to NaAc in water soluble assays compared to wild-type. Paper_evidence: WBPaper00031959
            Curator_confirmed: WBPerson712
        Variation_effect: Null: Paper_evidence: WBPaper00031959
            Curator_confirmed: WBPerson712
        Affected_by: Molecule: WBMol:00003571 Paper_evidence: WBPaper00031959
              Curator_confirmed: WBPerson712
        Phenotype_assay: Treatment: For the water soluble chemotaxis assay, radial gradients of NaCl were established by diffusion in the agar. Paper_evidence: WBPaper00031959
              Curator_confirmed: WBPerson712
      WBPhenotype:0001084 Paper_evidence: WBPaper00031959
        Curator_confirmed: WBPerson712
        Remark: Animals were completely defective in NaCl chemotaxis in water soluble assays. Paper_evidence: WBPaper00031959
            Curator_confirmed: WBPerson712
        Variation_effect: Null: Paper_evidence: WBPaper00031959
            Curator_confirmed: WBPerson712
        Affected_by: Molecule: WBMol:00003571 Paper_evidence: WBPaper00031959
              Curator_confirmed: WBPerson712
        Phenotype_assay: Treatment: For the water soluble chemotaxis assay, radial gradients of NaCl were established by diffusion in the agar. Paper_evidence: WBPaper00031959
              Curator_confirmed: WBPerson712
      WBPhenotype:0001435 Paper_evidence: WBPaper00031959
        Curator_confirmed: WBPerson712
        Remark: Animals showed a reduction in chemotaxis to ammonium chloride compared to wild-type and were significantly defective in comparison to positive control che-1(p679) animals. Paper_evidence: WBPaper00031959
            Curator_confirmed: WBPerson712
        Penetrance: Incomplete: Paper_evidence: WBPaper00031959
              Curator_confirmed: WBPerson712
        Variation_effect: Null: Paper_evidence: WBPaper00031959
            Curator_confirmed: WBPerson712
        Affected_by: Molecule: WBMol:00002092 Paper_evidence: WBPaper00031959
              Curator_confirmed: WBPerson712
        Phenotype_assay: Treatment: For the soluble assay, radial gradients of NH4Cl were established by diffusion in the agar. Paper_evidence: WBPaper00031959
              Curator_confirmed: WBPerson712
      WBPhenotype:0001438 Paper_evidence: WBPaper00031959
        Curator_confirmed: WBPerson712
        Remark: Animals are defective in chemotaxis to ammonium acetate as an odorant, compared to wild-type. Paper_evidence: WBPaper00031959
            Curator_confirmed: WBPerson712
        Variation_effect: Null: Paper_evidence: WBPaper00031959
            Curator_confirmed: WBPerson712
        Affected_by: Molecule: WBMol:00002790 Paper_evidence: WBPaper00031959
              Curator_confirmed: WBPerson712
        Phenotype_assay: Treatment: For the odorant assay, a droplet of NH4Ac (10 mL, 7.5 M) was suspended from the lid of the plate. Paper_evidence: WBPaper00031959
              Curator_confirmed: WBPerson712
      WBPhenotype:0001441 Paper_evidence: WBPaper00031959
        Curator_confirmed: WBPerson712
        Remark: Animals showed significantly reduced chemotaxis to ammonium acetate compared to wild-type animals. Paper_evidence: WBPaper00031959
            Curator_confirmed: WBPerson712
        Variation_effect: Null: Paper_evidence: WBPaper00031959
            Curator_confirmed: WBPerson712
        Affected_by: Molecule: WBMol:00002790 Paper_evidence: WBPaper00031959
              Curator_confirmed: WBPerson712
        Phenotype_assay: Treatment: For the water soluble chemotaxis assay, radial gradients of NH4Ac were established by diffusion in the agar. Paper_evidence: WBPaper00031959
              Curator_confirmed: WBPerson712
      WBPhenotype:0001442 Paper_evidence: WBPaper00031959
        Curator_confirmed: WBPerson712
        Remark: Animals showed a reduction in chemotaxis to sodium acetate compared to wild-type animals but, animals still showed residual positive chemotaxis similar to che-1(p679). Paper_evidence: WBPaper00031959
            Curator_confirmed: WBPerson712
        Penetrance: Incomplete: Paper_evidence: WBPaper00031959
              Curator_confirmed: WBPerson712
        Variation_effect: Null: Paper_evidence: WBPaper00031959
            Curator_confirmed: WBPerson712
        Affected_by: Molecule: WBMol:00004924 Paper_evidence: WBPaper00031959
              Curator_confirmed: WBPerson712
        Phenotype_assay: Treatment: For the soluble assay, radial gradients of NaAc were established by diffusion in the agar. Paper_evidence: WBPaper00031959
              Curator_confirmed: WBPerson712
      WBPhenotype:0001484 Paper_evidence: WBPaper00031959
        Curator_confirmed: WBPerson712
        Remark: Animals showed significantly reduced chemotaxis to ammonium acetate in both the soluble and odorant assays, compared to wild-type animals. Paper_evidence: WBPaper00031959
            Curator_confirmed: WBPerson712
        Variation_effect: Null: Paper_evidence: WBPaper00031959
            Curator_confirmed: WBPerson712
        Affected_by: Molecule: WBMol:00002790 Paper_evidence: WBPaper00031959
              Curator_confirmed: WBPerson712
        Phenotype_assay: Treatment: Animals were tested in both soluble and odorant chemotaxis assays. For the soluble assay, radial gradients of NH4Ac were established by diffusion in the agar. For the odorant assay, a droplet of NH4Ac (10 mL, 7.5 M) was suspended from the lid of the plate. Paper_evidence: WBPaper00031959
              Curator_confirmed: WBPerson712
      WBPhenotype:0001738 Paper_evidence: WBPaper00031959
        Curator_confirmed: WBPerson712
        Remark: Animals were defective in ammonium chemotaxis in water soluble assays when compared to che-1(p679) positive control animals. Paper_evidence: WBPaper00031959
            Curator_confirmed: WBPerson712
        Variation_effect: Null: Paper_evidence: WBPaper00031959
            Curator_confirmed: WBPerson712
        Affected_by: Molecule: WBMol:00002091 Paper_evidence: WBPaper00031959
              Curator_confirmed: WBPerson712
        Phenotype_assay: Treatment: For the water soluble chemotaxis assay, radial gradients of NH4Cl were established by diffusion in the agar. Paper_evidence: WBPaper00031959
              Curator_confirmed: WBPerson712
    Phenotype_not_observed: WBPhenotype:0001736 Paper_evidence: WBPaper00031959
        Curator_confirmed: WBPerson712
        Remark: Animals showed no defect in acetate chemotaxis in water soluble assays when compared to che-1(p679) positive control animals. Paper_evidence: WBPaper00031959
            Curator_confirmed: WBPerson712
        Variation_effect: Null: Paper_evidence: WBPaper00031959
            Curator_confirmed: WBPerson712
        Affected_by: Molecule: WBMol:00005057 Paper_evidence: WBPaper00031959
              Curator_confirmed: WBPerson712
        Phenotype_assay: Treatment: For the water soluble chemotaxis assay, radial gradients of NaAc were established by diffusion in the agar. Paper_evidence: WBPaper00031959
              Curator_confirmed: WBPerson712
  Reference: WBPaper00031959
  Method: Allele