WormBase Tree Display for Variation: WBVar00249337

WBVar00249337 Name: Public_name: tm288
    HGVSg: CHROMOSOME_I:g.6322687_6324682del
  Sequence_details: SMap: S_parent: Sequence: F26B1
    Flanking_sequences: tgtatccacgtggacgacgacggaatccgt ttatcactcataccagaaaggtgctgaaga
    Mapping_target: F26B1
    Source_location: 7 CHROMOSOME_I 6322686 6324683 Inferred_automatically: National_Bioresource_Project
    Type_of_mutation: Deletion
    PCR_product: tm288_external
      tm288_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Laboratory: FX
    Author: Mitani S
    DB_info: Database: National_Bioresource_Project seq 288
    NBP_allele
    Status: Live
  Affects: Gene: WBGene00002601
    Transcript: F26B1.7.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,5_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        cDNA_position: ?-520
        CDS_position: ?-484
        Protein_position: ?-162
        Intron_number: 2-4/8
        Exon_number: 1-5/9
  Isolation: Mutagen: TMP/UV
  Genetics: Map: I
  Description: Phenotype: WBPhenotype:0000050 Paper_evidence: WBPaper00036106
        Curator_confirmed: WBPerson2021
        Remark: Homozygous mutants are embryonic lethal Paper_evidence: WBPaper00036106
            Curator_confirmed: WBPerson2021
      WBPhenotype:0000062 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson48
        Remark: Classified as lethal OR sterile by the National Bioresource Project of Japan. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson48
            Laboratory_evidence: FX
      WBPhenotype:0000095 Paper_evidence: WBPaper00036106
        Curator_confirmed: WBPerson2021
        Remark: Mutants displayed M lineage phenotypes Paper_evidence: WBPaper00036106
            Curator_confirmed: WBPerson2021
      WBPhenotype:0000414 Paper_evidence: WBPaper00036106
        Curator_confirmed: WBPerson2021
        Remark: Animals have extra egl-15::gfp-positive sex muscles Paper_evidence: WBPaper00036106
            Curator_confirmed: WBPerson2021
      WBPhenotype:0000688 Paper_evidence: WBPaper00036106
        Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson48
          WBPerson2021
        Remark: Classified as lethal OR sterile by the National Bioresource Project of Japan. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson48
            Laboratory_evidence: FX
          Some mutants survive to become sterile adults Paper_evidence: WBPaper00036106
            Curator_confirmed: WBPerson2021
      WBPhenotype:0000852 Paper_evidence: WBPaper00036106
        Curator_confirmed: WBPerson2021
        Remark: Animals lack functional embryonic and M-derived CCs Paper_evidence: WBPaper00036106
            Curator_confirmed: WBPerson2021
  Reference: WBPaper00036106
  Remark: 14526/14527-16522/16523 (1996 bp deletion)
    This knockout was generated by the National Bioresource Project, Tokyo, Japan, which is part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence: WBPaper00041807
  Method: NBP_knockout_allele