WormBase Tree Display for Variation: WBVar00249339

WBVar00249339 Name: Public_name: tm290
    Other_name (18)
    HGVSg: CHROMOSOME_III:g.7629673_7630276del
  Sequence_details: SMap: S_parent: Sequence: ZK783
    Flanking_sequences: gatgaggatcttatggaagaaggatctggg ctgattcgcttacagaaggatccggatctg
    Mapping_target: ZK783
    Source_location: 7 CHROMOSOME_III 7629672 7630277 Inferred_automatically: National_Bioresource_Project
    Type_of_mutation: Deletion
    PCR_product: tm290_external
      tm290_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Laboratory: FX
    Author: Mitani S
    DB_info: Database: National_Bioresource_Project seq 290
    NBP_allele
    Status: Live
  Affects: Gene: WBGene00022816
    Transcript: ZK783.1f.1 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: ZK783.1f.1:c.2137_2740del
        HGVSp: CE47720:p.Ser713LeufsTer225
        cDNA_position: 2137-2740
        CDS_position: 2137-2740
        Protein_position: 713-914
        Exon_number: 8/23
        Codon_change: TCTTGGAGTACGACTATCAATGGAACAGGAATTACTGGATCCCCTAGATCAGAGGGTACAATCAGAGTTAGAATTACAACATTAGGAGAGGATGGTGAACCAGAAACCGCAACAAAGCCAGGAATCAGTGCACCTGACAAAACTGGAGAAGGTTCAAAAACTGAGAGTGACGGAGAAGAGAAATTGACTGTTGAAAAAGATGGGAAAGAGGCACAGTCGTCTGGATCAAGTGCTACATCATCTGGAAAAAAATCCGAAGCGACATCAGGATCTTCTAGCTCTTCTGCAAAATCTGGGACCGGATCGGAAGCTTCTGGATCTTCTGGAGCTAGTTCATCTTCCGGATCAGGAGTTTCGGGAGAGTCTGGATCATCGGTTTCAACAGAGTCTGGAAGCTTTGGAACCTCTTCTAGTGGATCTGTTGGATCAGAAGCAACTGGATCGACAGGAGTTGACGGATCTGAATCAGGGAAGCCATCTAAATCATCAACTGAGGAAAAATTGCCATTTACCAAAAACGGGGAAAAATCTCCAATATCTGGTTCGGATACAACCGGCAAAGAATCCTCAGAAGAAACTACTTCGAGAAAACCTATCGAAGGATct/ct
        Amino_acid_change: SWSTTINGTGITGSPRSEGTIRVRITTLGEDGEPETATKPGISAPDKTGEGSKTESDGEEKLTVEKDGKEAQSSGSSATSSGKKSEATSGSSSSSAKSGTGSEASGSSGASSSSGSGVSGESGSSVSTESGSFGTSSSGSVGSEATGSTGVDGSESGKPSKSSTEEKLPFTKNGEKSPISGSDTTGKESSEETTSRKPIEGS/X
      ZK783.1j.1 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: ZK783.1j.1:c.2137_2740del
        HGVSp: CE47737:p.Ser713LeufsTer225
        cDNA_position: 2137-2740
        CDS_position: 2137-2740
        Protein_position: 713-914
        Exon_number: 8/15
        Codon_change: TCTTGGAGTACGACTATCAATGGAACAGGAATTACTGGATCCCCTAGATCAGAGGGTACAATCAGAGTTAGAATTACAACATTAGGAGAGGATGGTGAACCAGAAACCGCAACAAAGCCAGGAATCAGTGCACCTGACAAAACTGGAGAAGGTTCAAAAACTGAGAGTGACGGAGAAGAGAAATTGACTGTTGAAAAAGATGGGAAAGAGGCACAGTCGTCTGGATCAAGTGCTACATCATCTGGAAAAAAATCCGAAGCGACATCAGGATCTTCTAGCTCTTCTGCAAAATCTGGGACCGGATCGGAAGCTTCTGGATCTTCTGGAGCTAGTTCATCTTCCGGATCAGGAGTTTCGGGAGAGTCTGGATCATCGGTTTCAACAGAGTCTGGAAGCTTTGGAACCTCTTCTAGTGGATCTGTTGGATCAGAAGCAACTGGATCGACAGGAGTTGACGGATCTGAATCAGGGAAGCCATCTAAATCATCAACTGAGGAAAAATTGCCATTTACCAAAAACGGGGAAAAATCTCCAATATCTGGTTCGGATACAACCGGCAAAGAATCCTCAGAAGAAACTACTTCGAGAAAACCTATCGAAGGATct/ct
        Amino_acid_change: SWSTTINGTGITGSPRSEGTIRVRITTLGEDGEPETATKPGISAPDKTGEGSKTESDGEEKLTVEKDGKEAQSSGSSATSSGKKSEATSGSSSSSAKSGTGSEASGSSGASSSSGSGVSGESGSSVSTESGSFGTSSSGSVGSEATGSTGVDGSESGKPSKSSTEEKLPFTKNGEKSPISGSDTTGKESSEETTSRKPIEGS/X
      ZK783.1g.1 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: ZK783.1g.1:c.2137_2740del
        HGVSp: CE47732:p.Ser713LeufsTer225
        cDNA_position: 2137-2740
        CDS_position: 2137-2740
        Protein_position: 713-914
        Exon_number: 8/23
        Codon_change: TCTTGGAGTACGACTATCAATGGAACAGGAATTACTGGATCCCCTAGATCAGAGGGTACAATCAGAGTTAGAATTACAACATTAGGAGAGGATGGTGAACCAGAAACCGCAACAAAGCCAGGAATCAGTGCACCTGACAAAACTGGAGAAGGTTCAAAAACTGAGAGTGACGGAGAAGAGAAATTGACTGTTGAAAAAGATGGGAAAGAGGCACAGTCGTCTGGATCAAGTGCTACATCATCTGGAAAAAAATCCGAAGCGACATCAGGATCTTCTAGCTCTTCTGCAAAATCTGGGACCGGATCGGAAGCTTCTGGATCTTCTGGAGCTAGTTCATCTTCCGGATCAGGAGTTTCGGGAGAGTCTGGATCATCGGTTTCAACAGAGTCTGGAAGCTTTGGAACCTCTTCTAGTGGATCTGTTGGATCAGAAGCAACTGGATCGACAGGAGTTGACGGATCTGAATCAGGGAAGCCATCTAAATCATCAACTGAGGAAAAATTGCCATTTACCAAAAACGGGGAAAAATCTCCAATATCTGGTTCGGATACAACCGGCAAAGAATCCTCAGAAGAAACTACTTCGAGAAAACCTATCGAAGGATct/ct
        Amino_acid_change: SWSTTINGTGITGSPRSEGTIRVRITTLGEDGEPETATKPGISAPDKTGEGSKTESDGEEKLTVEKDGKEAQSSGSSATSSGKKSEATSGSSSSSAKSGTGSEASGSSGASSSSGSGVSGESGSSVSTESGSFGTSSSGSVGSEATGSTGVDGSESGKPSKSSTEEKLPFTKNGEKSPISGSDTTGKESSEETTSRKPIEGS/X
      ZK783.1h.1 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: ZK783.1h.1:c.2137_2740del
        HGVSp: CE47716:p.Ser713LeufsTer225
        cDNA_position: 2137-2740
        CDS_position: 2137-2740
        Protein_position: 713-914
        Exon_number: 8/22
        Codon_change: TCTTGGAGTACGACTATCAATGGAACAGGAATTACTGGATCCCCTAGATCAGAGGGTACAATCAGAGTTAGAATTACAACATTAGGAGAGGATGGTGAACCAGAAACCGCAACAAAGCCAGGAATCAGTGCACCTGACAAAACTGGAGAAGGTTCAAAAACTGAGAGTGACGGAGAAGAGAAATTGACTGTTGAAAAAGATGGGAAAGAGGCACAGTCGTCTGGATCAAGTGCTACATCATCTGGAAAAAAATCCGAAGCGACATCAGGATCTTCTAGCTCTTCTGCAAAATCTGGGACCGGATCGGAAGCTTCTGGATCTTCTGGAGCTAGTTCATCTTCCGGATCAGGAGTTTCGGGAGAGTCTGGATCATCGGTTTCAACAGAGTCTGGAAGCTTTGGAACCTCTTCTAGTGGATCTGTTGGATCAGAAGCAACTGGATCGACAGGAGTTGACGGATCTGAATCAGGGAAGCCATCTAAATCATCAACTGAGGAAAAATTGCCATTTACCAAAAACGGGGAAAAATCTCCAATATCTGGTTCGGATACAACCGGCAAAGAATCCTCAGAAGAAACTACTTCGAGAAAACCTATCGAAGGATct/ct
        Amino_acid_change: SWSTTINGTGITGSPRSEGTIRVRITTLGEDGEPETATKPGISAPDKTGEGSKTESDGEEKLTVEKDGKEAQSSGSSATSSGKKSEATSGSSSSSAKSGTGSEASGSSGASSSSGSGVSGESGSSVSTESGSFGTSSSGSVGSEATGSTGVDGSESGKPSKSSTEEKLPFTKNGEKSPISGSDTTGKESSEETTSRKPIEGS/X
      ZK783.1d.1 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: ZK783.1d.1:c.2137_2740del
        HGVSp: CE47697:p.Ser713LeufsTer225
        cDNA_position: 2137-2740
        CDS_position: 2137-2740
        Protein_position: 713-914
        Exon_number: 8/23
        Codon_change: TCTTGGAGTACGACTATCAATGGAACAGGAATTACTGGATCCCCTAGATCAGAGGGTACAATCAGAGTTAGAATTACAACATTAGGAGAGGATGGTGAACCAGAAACCGCAACAAAGCCAGGAATCAGTGCACCTGACAAAACTGGAGAAGGTTCAAAAACTGAGAGTGACGGAGAAGAGAAATTGACTGTTGAAAAAGATGGGAAAGAGGCACAGTCGTCTGGATCAAGTGCTACATCATCTGGAAAAAAATCCGAAGCGACATCAGGATCTTCTAGCTCTTCTGCAAAATCTGGGACCGGATCGGAAGCTTCTGGATCTTCTGGAGCTAGTTCATCTTCCGGATCAGGAGTTTCGGGAGAGTCTGGATCATCGGTTTCAACAGAGTCTGGAAGCTTTGGAACCTCTTCTAGTGGATCTGTTGGATCAGAAGCAACTGGATCGACAGGAGTTGACGGATCTGAATCAGGGAAGCCATCTAAATCATCAACTGAGGAAAAATTGCCATTTACCAAAAACGGGGAAAAATCTCCAATATCTGGTTCGGATACAACCGGCAAAGAATCCTCAGAAGAAACTACTTCGAGAAAACCTATCGAAGGATct/ct
        Amino_acid_change: SWSTTINGTGITGSPRSEGTIRVRITTLGEDGEPETATKPGISAPDKTGEGSKTESDGEEKLTVEKDGKEAQSSGSSATSSGKKSEATSGSSSSSAKSGTGSEASGSSGASSSSGSGVSGESGSSVSTESGSFGTSSSGSVGSEATGSTGVDGSESGKPSKSSTEEKLPFTKNGEKSPISGSDTTGKESSEETTSRKPIEGS/X
      ZK783.1e.1 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: ZK783.1e.1:c.2137_2740del
        HGVSp: CE44082:p.Ser713LeufsTer225
        cDNA_position: 2137-2740
        CDS_position: 2137-2740
        Protein_position: 713-914
        Exon_number: 8/23
        Codon_change: TCTTGGAGTACGACTATCAATGGAACAGGAATTACTGGATCCCCTAGATCAGAGGGTACAATCAGAGTTAGAATTACAACATTAGGAGAGGATGGTGAACCAGAAACCGCAACAAAGCCAGGAATCAGTGCACCTGACAAAACTGGAGAAGGTTCAAAAACTGAGAGTGACGGAGAAGAGAAATTGACTGTTGAAAAAGATGGGAAAGAGGCACAGTCGTCTGGATCAAGTGCTACATCATCTGGAAAAAAATCCGAAGCGACATCAGGATCTTCTAGCTCTTCTGCAAAATCTGGGACCGGATCGGAAGCTTCTGGATCTTCTGGAGCTAGTTCATCTTCCGGATCAGGAGTTTCGGGAGAGTCTGGATCATCGGTTTCAACAGAGTCTGGAAGCTTTGGAACCTCTTCTAGTGGATCTGTTGGATCAGAAGCAACTGGATCGACAGGAGTTGACGGATCTGAATCAGGGAAGCCATCTAAATCATCAACTGAGGAAAAATTGCCATTTACCAAAAACGGGGAAAAATCTCCAATATCTGGTTCGGATACAACCGGCAAAGAATCCTCAGAAGAAACTACTTCGAGAAAACCTATCGAAGGATct/ct
        Amino_acid_change: SWSTTINGTGITGSPRSEGTIRVRITTLGEDGEPETATKPGISAPDKTGEGSKTESDGEEKLTVEKDGKEAQSSGSSATSSGKKSEATSGSSSSSAKSGTGSEASGSSGASSSSGSGVSGESGSSVSTESGSFGTSSSGSVGSEATGSTGVDGSESGKPSKSSTEEKLPFTKNGEKSPISGSDTTGKESSEETTSRKPIEGS/X
      ZK783.1k.1 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: ZK783.1k.1:c.2143_2746del
        HGVSp: CE47705:p.Ser715LeufsTer225
        cDNA_position: 2143-2746
        CDS_position: 2143-2746
        Protein_position: 715-916
        Exon_number: 8/25
        Codon_change: TCTTGGAGTACGACTATCAATGGAACAGGAATTACTGGATCCCCTAGATCAGAGGGTACAATCAGAGTTAGAATTACAACATTAGGAGAGGATGGTGAACCAGAAACCGCAACAAAGCCAGGAATCAGTGCACCTGACAAAACTGGAGAAGGTTCAAAAACTGAGAGTGACGGAGAAGAGAAATTGACTGTTGAAAAAGATGGGAAAGAGGCACAGTCGTCTGGATCAAGTGCTACATCATCTGGAAAAAAATCCGAAGCGACATCAGGATCTTCTAGCTCTTCTGCAAAATCTGGGACCGGATCGGAAGCTTCTGGATCTTCTGGAGCTAGTTCATCTTCCGGATCAGGAGTTTCGGGAGAGTCTGGATCATCGGTTTCAACAGAGTCTGGAAGCTTTGGAACCTCTTCTAGTGGATCTGTTGGATCAGAAGCAACTGGATCGACAGGAGTTGACGGATCTGAATCAGGGAAGCCATCTAAATCATCAACTGAGGAAAAATTGCCATTTACCAAAAACGGGGAAAAATCTCCAATATCTGGTTCGGATACAACCGGCAAAGAATCCTCAGAAGAAACTACTTCGAGAAAACCTATCGAAGGATct/ct
        Amino_acid_change: SWSTTINGTGITGSPRSEGTIRVRITTLGEDGEPETATKPGISAPDKTGEGSKTESDGEEKLTVEKDGKEAQSSGSSATSSGKKSEATSGSSSSSAKSGTGSEASGSSGASSSSGSGVSGESGSSVSTESGSFGTSSSGSVGSEATGSTGVDGSESGKPSKSSTEEKLPFTKNGEKSPISGSDTTGKESSEETTSRKPIEGS/X
      ZK783.1a.1 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: ZK783.1a.1:c.2137_2740del
        HGVSp: CE47717:p.Ser713LeufsTer225
        cDNA_position: 2137-2740
        CDS_position: 2137-2740
        Protein_position: 713-914
        Exon_number: 8/26
        Codon_change: TCTTGGAGTACGACTATCAATGGAACAGGAATTACTGGATCCCCTAGATCAGAGGGTACAATCAGAGTTAGAATTACAACATTAGGAGAGGATGGTGAACCAGAAACCGCAACAAAGCCAGGAATCAGTGCACCTGACAAAACTGGAGAAGGTTCAAAAACTGAGAGTGACGGAGAAGAGAAATTGACTGTTGAAAAAGATGGGAAAGAGGCACAGTCGTCTGGATCAAGTGCTACATCATCTGGAAAAAAATCCGAAGCGACATCAGGATCTTCTAGCTCTTCTGCAAAATCTGGGACCGGATCGGAAGCTTCTGGATCTTCTGGAGCTAGTTCATCTTCCGGATCAGGAGTTTCGGGAGAGTCTGGATCATCGGTTTCAACAGAGTCTGGAAGCTTTGGAACCTCTTCTAGTGGATCTGTTGGATCAGAAGCAACTGGATCGACAGGAGTTGACGGATCTGAATCAGGGAAGCCATCTAAATCATCAACTGAGGAAAAATTGCCATTTACCAAAAACGGGGAAAAATCTCCAATATCTGGTTCGGATACAACCGGCAAAGAATCCTCAGAAGAAACTACTTCGAGAAAACCTATCGAAGGATct/ct
        Amino_acid_change: SWSTTINGTGITGSPRSEGTIRVRITTLGEDGEPETATKPGISAPDKTGEGSKTESDGEEKLTVEKDGKEAQSSGSSATSSGKKSEATSGSSSSSAKSGTGSEASGSSGASSSSGSGVSGESGSSVSTESGSFGTSSSGSVGSEATGSTGVDGSESGKPSKSSTEEKLPFTKNGEKSPISGSDTTGKESSEETTSRKPIEGS/X
      ZK783.1b.1 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: ZK783.1b.1:c.2137_2740del
        HGVSp: CE47727:p.Ser713LeufsTer225
        cDNA_position: 2137-2740
        CDS_position: 2137-2740
        Protein_position: 713-914
        Exon_number: 8/25
        Codon_change: TCTTGGAGTACGACTATCAATGGAACAGGAATTACTGGATCCCCTAGATCAGAGGGTACAATCAGAGTTAGAATTACAACATTAGGAGAGGATGGTGAACCAGAAACCGCAACAAAGCCAGGAATCAGTGCACCTGACAAAACTGGAGAAGGTTCAAAAACTGAGAGTGACGGAGAAGAGAAATTGACTGTTGAAAAAGATGGGAAAGAGGCACAGTCGTCTGGATCAAGTGCTACATCATCTGGAAAAAAATCCGAAGCGACATCAGGATCTTCTAGCTCTTCTGCAAAATCTGGGACCGGATCGGAAGCTTCTGGATCTTCTGGAGCTAGTTCATCTTCCGGATCAGGAGTTTCGGGAGAGTCTGGATCATCGGTTTCAACAGAGTCTGGAAGCTTTGGAACCTCTTCTAGTGGATCTGTTGGATCAGAAGCAACTGGATCGACAGGAGTTGACGGATCTGAATCAGGGAAGCCATCTAAATCATCAACTGAGGAAAAATTGCCATTTACCAAAAACGGGGAAAAATCTCCAATATCTGGTTCGGATACAACCGGCAAAGAATCCTCAGAAGAAACTACTTCGAGAAAACCTATCGAAGGATct/ct
        Amino_acid_change: SWSTTINGTGITGSPRSEGTIRVRITTLGEDGEPETATKPGISAPDKTGEGSKTESDGEEKLTVEKDGKEAQSSGSSATSSGKKSEATSGSSSSSAKSGTGSEASGSSGASSSSGSGVSGESGSSVSTESGSFGTSSSGSVGSEATGSTGVDGSESGKPSKSSTEEKLPFTKNGEKSPISGSDTTGKESSEETTSRKPIEGS/X
  Isolation: Mutagen: TMP/UV
  Genetics: Map: III
    Mapping_data: In_multi_point: 5355
  Description: Phenotype: WBPhenotype:0000062 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson48
        Remark: Classified as lethal OR sterile by the National Bioresource Project of Japan. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson48
            Laboratory_evidence: FX
      WBPhenotype:0000638 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson2021
        Remark: Comments to the National Bioresource Project of Japan: Dr. A. Frand: Mlt. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson2021
            Laboratory_evidence: FX
      WBPhenotype:0000688 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson48
        Remark: Classified as lethal OR sterile by the National Bioresource Project of Japan. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson48
            Laboratory_evidence: FX
    Phenotype_not_observed: WBPhenotype:0000195 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson48
        Remark: Comment from Dr. K. Nishiwaki to the National Bioresource Project of Japan: normal DTC migration. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson48
  Remark: 3846/3847-4450/4451 (604 bp deletion)
    This knockout was generated by the National Bioresource Project, Tokyo, Japan, which is part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence: WBPaper00041807
  Method: NBP_knockout_allele