WormBase Tree Display for Variation: WBVar00249409

WBVar00249409 Name: Public_name: tm361
    Other_name: C18A3.5a.1:c.241-136_476del
      C18A3.5c.1:c.304_*228del
      C18A3.5b.1:c.240+201_380del
    HGVSg: CHROMOSOME_II:g.5713715_5714293del
  Sequence_details: SMap: S_parent: Sequence: C18A3
    Flanking_sequences: tcacggatcactttggcgtccgaaacatct ctgtctcagtgtcggtgtggattggttgcc
    Mapping_target: C18A3
    Source_location: 7 CHROMOSOME_II 5713714 5714294 Inferred_automatically: National_Bioresource_Project
    Type_of_mutation: Deletion
    PCR_product: tm361_external
      tm361_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Laboratory: FX
    Author: Mitani S
    DB_info: Database: National_Bioresource_Project seq 361
    NBP_allele
    Status: Live
  Affects: Gene: WBGene00015943
    Transcript: C18A3.5a.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: C18A3.5a.1:c.241-136_476del
        cDNA_position: ?-494
        CDS_position: ?-476
        Protein_position: ?-159
        Intron_number: 3-4/7
        Exon_number: 4-5/8
      C18A3.5c.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,stop_lost,3_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: C18A3.5c.1:c.304_*228del
        cDNA_position: 322-558
        CDS_position: 304-?
        Protein_position: 102-?
        Intron_number: 4-6/8
        Exon_number: 4-7/9
      C18A3.5b.1 VEP_consequence: splice_acceptor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: C18A3.5b.1:c.240+201_380del
        cDNA_position: ?-398
        CDS_position: ?-380
        Protein_position: ?-127
        Intron_number: 3/5
        Exon_number: 4/6
    Interactor: WBInteraction000521770
  Isolation: Mutagen: TMP/UV
  Genetics: Map: II
  Description: Phenotype: WBPhenotype:0000182 Paper_evidence: WBPaper00044006
        Curator_confirmed: WBPerson9883
      WBPhenotype:0000186 Paper_evidence: WBPaper00044006
        Curator_confirmed: WBPerson9883
      WBPhenotype:0000668 Paper_evidence: WBPaper00044006
        Curator_confirmed: WBPerson9883
      WBPhenotype:0000848 Paper_evidence: WBPaper00045542
        Curator_confirmed: WBPerson1724
      WBPhenotype:0001015 Paper_evidence: WBPaper00045542
        Curator_confirmed: WBPerson1724
      WBPhenotype:0001384 Paper_evidence: WBPaper00044006
        Curator_confirmed: WBPerson9883
      WBPhenotype:0001756 Paper_evidence: WBPaper00044006
        Curator_confirmed: WBPerson9883
      WBPhenotype:0001925 Paper_evidence: WBPaper00044006
        Curator_confirmed: WBPerson9883
    Phenotype_not_observed: WBPhenotype:0000062 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Classified as homozygous viable by the National Bioresource Project of Japan. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
            Laboratory_evidence: FX
      WBPhenotype:0000643 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Comment from Dr. H. Zhang: normal locomotion. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
      WBPhenotype:0000688 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Comment from Dr. H. Zhang: fertile Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
      WBPhenotype:0000812 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Comment from Dr. T. Schedl to the National Bioresource Project of Japan: no germline phenotype. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
      WBPhenotype:0002259 Paper_evidence: WBPaper00046432
        Curator_confirmed: WBPerson712
        Remark: Mutants do not exhibit a reduction in PVD neuron terminal dendrites. Paper_evidence: WBPaper00046432
            Curator_confirmed: WBPerson712
        EQ_annotations: Anatomy_term: WBbt:0006831 PATO:0000460 Paper_evidence: WBPaper00046432
                Curator_confirmed: WBPerson712
          GO_term: GO:0044292 PATO:0001997 Paper_evidence: WBPaper00046432
                Curator_confirmed: WBPerson712
  Reference: WBPaper00044006
    WBPaper00045542
    WBPaper00046432
  Remark: 12290/12291-12869/12870 (579 bp deletion)
    This knockout was generated by the National Bioresource Project, Tokyo, Japan, which is part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence: WBPaper00041807
  Method: NBP_knockout_allele